Synthesis and Biological Evaluation of New Quinoline and Anthranilic Acid Derivatives as Potential Quorum Sensing Inhibitors. [PDF]
Perković I +8 more
europepmc +1 more source
ABSTRACT Disease outbreaks and the associated reliance on antibiotics pose major constraints to the sustainability of modern aquaculture. As regulatory pressures increase and consumer demand shifts toward residue‐free production, diverse biological interventions are gaining prominence as viable alternatives to chemotherapeutics.
Mustafa Öz +5 more
wiley +1 more source
With the rise in antibiotic resistance, quorum sensing inhibition has emerged as a possible alternative to classical antibiotic therapy. Quorum sensing is density-dependent communication between bacteria that allows the bacteria to coordinate gene ...
Kemp, Chesley Anne +4 more
core
CryoFluorSEM – A new approach for fluorescence and EM imaging of cryofractured plant samples
Abstract Cryo‐scanning electron microscopy (CryoSEM) permits the preparation and detailed imaging of bulky samples while keeping them in a hydrated state. For plant biology, cryofractures give information on cell ultrastructure and tissue organisation within a much larger context that is the whole organ or organism.
Raymond Wightman +6 more
wiley +1 more source
Virtual screening-based discovery of AI-2 quorum sensing inhibitors that interact with an allosteric hydrophobic site of LsrK and their functional evaluation. [PDF]
Shi Q +9 more
europepmc +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger +5 more
wiley +1 more source
Potent pan-group quorum sensing inhibitors in Staphylococcus aureus revealed by N-terminal tailoring of peptidomimetics. [PDF]
Zhao K, Vasquez JK, Blackwell HE.
europepmc +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
The AhR ligand phthiocol and vitamin K analogs as Pseudomonas aeruginosa quorum sensing inhibitors. [PDF]
Jia T +12 more
europepmc +1 more source
Nitric Oxide Tunes Secreted Metabolite Bioactivity
Pseudomonas aeruginosa produces phenazine metabolites that can react with nitric oxide (·NO) to form nitrosylated compounds. The formation of these metabolites results in rapid loss in P. aeruginosa viability and diminishes phenazine antimicrobial activity against other organisms, including Staphylococcus aureus. ABSTRACT The radical nitric oxide (·NO)
Zachery R. Lonergan +7 more
wiley +1 more source

