Results 71 to 80 of about 13,305 (277)

Aromatherapeutic Antibacterials: Comparative Study of 40 Essential Oils and Their Biofilm Inhibition in Pseudomonas aeruginosa ATCC9027

Hayati Journal of Biosciences
Growing evidence suggests that biofilm formation in Pseudomonas aeruginosa (PA) results from quorum sensing, reducing bacterial sensitivity to antibiotics and fostering the development of antibiotic-resistant strains.
Nur Aziz, Rollando, Eva Monica, F.X Haryanto Susanto   +3 more
doaj   +1 more source

Quorum sensing inhibitors of bacteria Streptococcus pneumoniae

Zdorovʹe Rebenka, 2019
The scientific review systematizes information on LuxS/AI-2 and ComABCDE quorum sensing systems of bacteria Streptococcus pneumoniae. It is emphasized that biofilms of bacteria Streptococcus pneumoniae are one of the mechanisms of antibiotic resistance ...
А.Е. Abaturov, Т.А. Kryuchko
doaj   +1 more source

The Effects of Quorum Sensing Inhibitors on Multispecies Biofilms of the Oral Cavity [PDF]

, 2018
Biofilms are defined as assemblages of one or more species of surface-associated bacterial cells and other microorganisms encapsulated by a self-produced extracellular matrix consisting primarily of polysaccharides, extracellular DNA, and proteins that ...
Kyazze, G., Anyogu, A., Garner, C., Keshavarz, T.   +3 more
core  

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

In vitro reconstituted quorum sensing pathways enable rapid evaluation of quorum sensing inhibitors [PDF]

, 2021
ABSTRACT Quorum sensing, as inner- or inter-species microbial communication process orchestrated by diffusible autoinducers, typically results in collective pathogenic behaviours, being recognized as a promising druggable target for anti-virulence. Here, we reconstituted las and
openaire   +1 more source

Exploration of quorum sensing inhibition in gram positive bacterial pathogens using mass spectrometry [PDF]

, 2015
Antibiotics have been used as the primary treatment for bacterial infections since the 1940’s. Unfortunately, the use and misuse of antibiotics has led to the proliferation of antibiotic-resistant bacteria and resulted in the loss of antibiotic efficacy.
Todd, Daniel A., NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Quorum sensing inhibitors: how strong is the evidence?

, 2013
Because of its promising effect as an alternative to antibiotics, quorum sensing disruption is an intensively studied field, and there are many studies that describe the quorum sensing inhibitory activity of natural and synthetic compounds.
Defoirdt, Tom, Coenye, Tom, Brackman, Gilles   +2 more
core   +1 more source

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

Evaluation of Enoyl-Acyl Carrier Protein Reductase Inhibitors as Pseudomonas aeruginosa Quorum-Quenching Reagents

Molecules, 2010
Pseudomonas aeruginosa is an opportunistic pathogen which is responsible for a wide range of infections. Production of virulence factors and biofilm formation by P.
Søren Molin, Claus Sternberg, Yang Liu, Liang Yang   +3 more
doaj   +1 more source