Results 61 to 70 of about 1,465,833 (268)
Synthesis of majucin-type sesquiterpenes and immobilization and visualization of quorum sensing signaling molecules [PDF]
, 2014 The science of chemical biology is the ability to answer biological questions by analyzing living systems at the chemical level. Two entirely different approaches to reach this goal are presented in this thesis.
Gomes, José Rui
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Novel approaches for the design and discovery of quorum-sensing inhibitors [PDF]
Expert Opinion on Drug Discovery, 2014 The spread of antibiotic resistance, together with the lack of antibiotics based on novel molecular scaffolds, marks the so-called 'post-antibiotic era'. Interference with bacterial virulence has emerged as an attractive approach among the current potential strategies for developing new anti-infective drugs.
Sara, Scutera +2 more
openaire +2 more sources
The Collective Power of Bacteria as a Blueprint for Emergent Intelligence
Advanced Intelligent Systems, EarlyView.Small cells, powerful collectives. Bacteria demonstrate how sophisticated behaviors can emerge from many simple individuals working together. We explore the remarkable world of bacterial communities and the mechanisms that underpin their complex emergent behaviors, enabling impressive adaptability, robustness, and responsiveness to changing ...
Johanna A. Blee +2 more
wiley +1 more source
alpha-Hydroxyketone Synthesis and Sensing by Legionella and Vibrio [PDF]
, 2012 Bacteria synthesize and sense low molecular weight signaling molecules, termed autoinducers, to measure their population density and community complexity. One class of autoinducers, the α-hydroxyketones (AHKs), is produced and detected by the water-borne
Hubert Hilbi +3 more
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Molecules, 2010 Pseudomonas aeruginosa is an opportunistic pathogen which is responsible for a wide range of infections. Production of virulence factors and biofilm formation by P.
Søren Molin +3 more
doaj +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Bitter taste receptors (T2Rs) function in the innate immune defense of the sinonasal mucosa; however, the genetic association between the TAS2R gene family and chronic rhinosinusitis (CRS) remains understudied in Asian populations.
Rong‐San Jiang +6 more
wiley +1 more source
A novel two-component signal transduction system in propionibacterium acnes and its association with a putative extracellular signalling peptide [PDF]
, 2011 Propionibacterium acnes, a resident micro-organism of human skin, is thought to be involved in the development of inflammatory acne, which is an exclusive human disease affecting more than 80% of the whole population. Quorum sensing is the regulation of
Guan, Shuang
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In vitro reconstituted quorum sensing pathways enable rapid evaluation of quorum sensing inhibitors [PDF]
, 2021 ABSTRACT Quorum sensing, as inner- or inter-species microbial communication process orchestrated by diffusible autoinducers, typically results in collective pathogenic behaviours, being recognized as a promising druggable target for anti-virulence. Here, we reconstituted las and
openaire +1 more source
Advanced NanoBiomed Research, EarlyView.Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Quorum sensing in Porphyromonas gingivalis and oral microbial interactions: a scoping review
Frontiers in Oral HealthObjectivePorphyromonas gingivalis, a major periodontal pathogen, interacts with other oral microbes through quorum sensing, enhancing its growth and virulence, which contributes to periodontitis.
Zelda Ziyi Zhao +5 more
doaj +1 more source