Results 231 to 240 of about 43,185 (293)

Transparency of the environmental cost - benefits of research? The "ADESC - Academic Environmental SCore" for publication. [PDF]

Environ Health Prev Med
Descatha A, Savary D, Schnebelen C.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

How Do Clinicians Use Quotations in Goals of Care Notes? [PDF]

Chest
Piscitello GM, Ali R, Hauschildt K, Schell J.   +3 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Perceptions about using a patient portal to self-disclose HIV-related information to sexual partners: a qualitative study among adolescents and emerging adults living with HIV. [PDF]

AIDS Care
Jackman KM, Agwu A, Ohene-Kyei ET, Barfield A, Huettner S, Trent M.   +5 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

'We Did the Very Best We Could for the Residents': A Thematic Analysis of Work Experience in Swedish Nursing Homes During the COVID-19 Pandemic. [PDF]

Scand J Caring Sci
Carlsson V, Gustafsson IL, Berg Ljungdahl H, Bratt AS.   +3 more
europepmc   +1 more source

Perspectives of Women with Breast Cancer and Healthcare Providers Participating in an Adherence-Enhancing Program for Adjuvant Endocrine Therapy: A Qualitative Study. [PDF]

Curr Oncol
Turcotte V, Guillaumie L, Lemay M, Dionne A, Lemieux J, Labbé A, Gotay C, Guénette L, Lauzier S.   +8 more
europepmc   +1 more source

"I don't want to make trouble": Emotional Distress, Disconnection, and Loneliness Among Older People in China. [PDF]

J Gerontol B Psychol Sci Soc Sci
Gao Q, Prina M, Huang Y, Liu Z, Rozanova J, Mayston R.   +5 more
europepmc   +1 more source

Perspectives on Point-of-Care Ultrasonography Credentialing and Privileging: A Qualitative Study.

JAMA Netw Open
Conner SM, Anstey JE, Thomas MK, Carney PA, Fiore MD, Little CE, Jensen TP, Piro KM.   +7 more
europepmc   +1 more source