Results 181 to 190 of about 115,028 (266)

C2CD5 in noradrenergic neurons regulates thermogenesis and lipid homeostasis via norepinephrine secretion. [PDF]

iScience
Gavini CK, Labouèbe G, Gorostidi F, Mansuy-Aubert V.   +3 more
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

The effect of aerobic exercise with blood flow restriction on substrate utilization and energy expenditure. [PDF]

Front Sports Act Living
Lauver JD, Andrews N, Harris C, Zanchi NE, Johnson KE, Rotarius TR, Guilkey JP.   +6 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Impact of central adiposity on the heart rate and calorie estimation accuracy of diverse smartwatches and the resulting subjective exercise experience. [PDF]

Front Sports Act Living
Lertyongphati A, Udomkhwamsuk W, Amornrungrojanakul N, Suk-Ieam K, Khamyan W, Chaengchit P, Asawaponwiput W, Vichitkunakorn P, Surangsrirat D.   +8 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Ethinyl estradiol and levonorgestrel coadministration induces hypophagia and increases energy expenditure in female rats.

Endocrinology
Lacasse JM, Mohammad A, Montgomery KR, Bellaflor S, MacPherson REK, Galea LAM, McCormick CM.   +6 more
europepmc   +1 more source

Time series analysis of the new tiering pricing policy for generic medicines in South Korea. [PDF]

Front Pharmacol
Park CM, Song I, Kim DS.
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Stage-Stratified Economic Burden, Quality of Life, and Household Financial Coping Strategies in Diabetic Retinopathy in India: A Prospective Study With Exploratory Insurance Projections. [PDF]

Cureus
Tiruvengadakrishnan H, Ravi V, A S.
europepmc   +1 more source