Results 81 to 90 of about 115,028 (266)
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows +19 more
wiley +1 more source
Servitisation of manufacturing industry in Japan
The recent decline in the profitability of Japanese manufac‑ turers has led to ‘service innovation’ or servitisation – the development of advanced service businesses utilising infor‑ mation technology.
Noriyuki Shikata +2 more
doaj +1 more source
Determinants of corporate R&D expenditures: the role of taxes
AT_PUBLICATION
Wasiluk, Dorota, Białek-Jaworska, Anna
openaire +1 more source
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver +25 more
wiley +1 more source
Digital transformation has accelerated corporate innovation and strengthened competitive advantage, yet its impact on one of the most critical innovation inputs—corporate R&D expenditure—remains underexplored.
Tingqian Pu
doaj +1 more source
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
Immunoglobulin Depletion and Recovery Following Blinatumomab in Infants With KMT2A‐Rearranged ALL
ABSTRACT Adding blinatumomab to standard chemotherapy for infants with KMT2A‐rearranged acute B‐cell lymphoblastic leukemia (KMT2A‐r B‐ALL) improves outcomes. Although blinatumomab impairs immunoglobulin G (lgG) production, increasing infection susceptibility, IgG recovery remains poorly understood.
Miguel Vieira Martins +14 more
wiley +1 more source
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Technological investments and green energy production in Central and Eastern Europe
Objective: The article aims to examine the impact of technological investments on the development of wind energy and photovoltaics in Central and Eastern European countries (CEE) belonging to the EU.
Marcin Salamaga
doaj +1 more source
Total Factor Productivity and the R & D Expenditures
The total factor productivity (TFP) growth comes from improvements in the quality of labor and capital and from other sources of technological change, many of them in the form of externalities, spillovers, representing contributions of science and innovations in other enterprises, industries and countries.
openaire +1 more source

