Results 71 to 80 of about 640,932 (312)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Commonalities of standards certification and research and development as enablers of firms’ sustainable innovation and technological progress

open access: yesSustainable Technology and Entrepreneurship
Adoption of international standards and investment in research and development (R&D), can be seen as two possible paths to support enterprises’ sustainable innovation and technological progress.
Ján Hunady, Veronika Chyláková
doaj   +1 more source

Impact Assessment of Emissions Stabilization Scenarios with and without Induced Technological Change [PDF]

open access: yes
The main aim of this paper is to investigate quantitatively the economic impacts of emissions stabilization scenarios with and without the inclusion of induced technological change (ITC).
Claudia Kemfert, Truong P. Truong
core  

Aggregate R&D expenditure and endogenous economic growth. [PDF]

open access: yes, 1999
El objetivo de este trabajo es analizar teórica y empíricamente el papel que juega el gasto agregado en actividades de I+D en el crecimiento económico. Para ello, se propone una tecnología de innovación definida en unidades de gasto. De este modo se obtiene crecimiento endógeno sostenido aunque no exista crecimiento de la población. Esto
openaire   +2 more sources

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Induced Technological Change in a Multi-regional, Multi-sectoral Integrated Assessment Model (WIAGEM): Impact Assessment of Climate Policy Strategies [PDF]

open access: yes
This paper illustrates the representation of induced technological change in the multi- regional, multi-sectoral integrated assessment model WIAGEM. The main aim of this paper is to investigate quantitatively economic impacts of climate policy measures ...
Claudia Kemfert
core  

Divergent Expectations, R & D Expenditures and Technical Progress

open access: yes, 1980
This paper deals with the problem of whether diversity of beliefs or consensus leads to a higher level of R and D spending in an industry, or a faster rate of technical progress, or a lower price for the industry's product. The answer depends upon characteristics of the demand function for industry output as well as the density functions reflecting ...
Quirk, James P., Terasawa, Katsuaki
openaire   +2 more sources

The tax treatment of R&D expenditures of multinational enterprises [PDF]

open access: yesJournal of Public Economics, 1992
Abstract This paper investigates the tax treatment by national governments of R&D expenditures of multinational enterprises. In a noncooperative world, the international tax system is generally shown to discourage R&D investments by multinational firms.
openaire   +4 more sources

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

From campus to boardroom: CEO education and its influence on corporate policies

open access: yesFinancial Innovation
Unlike the previous literature, this study develops a comprehensive index of CEO education that considers levels and quality in bachelor’s, master’s, and doctoral (PhD) programs and examines how they relate to corporate policies such as capital ...
Mohamad Husam Helmi   +2 more
doaj   +1 more source

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