Results 91 to 100 of about 56,943 (309)

The Impacts of Firms' Research and Development Capacities on Innovation Development

open access: yesVerimlilik Dergisi
Purpose: The main objective of this study is to measure the effects of R&D capacities of firms operating in Türkiye, registered in Borsa Istanbul and having R&D centers on innovation development.Methodology: In this research, the panel data analysis ...
Saim Aydın, Erdinç Koç
doaj   +1 more source

Tax Incentives for Scientific and Technological Development: Experience of Foreign Countries and Russia [PDF]

open access: yesФинансовый журнал
The priority directions of the state policy of the Russian Federation on the development of investment activities in the country in projects related to the achievement of technological sovereignty and structural adaptation of the economy makes necessary ...
Ludmila V. Polezharova, Denis M. Volkov
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

R&D in Europe: Expenditures across Sectors, Regions and Firm Sizes. CEPS Paperbacks. February 2009 [PDF]

open access: yes, 2009
Europe’s growth outlook has weakened notably in the wake of the global financial crisis, and policy-makers are understandably preoccupied with achieving a near-term rebound.
Uppenberg, Kristian
core  

Quantification of technological learning by R&D and its application for renewable energy technologies

open access: yesNihon Kikai Gakkai ronbunshu, 2014
The paper examines the effects of research and development (R&D) on the capital cost reductions and the introduction of renewable energy technologies, namely solar photovoltaics (PV) and wind technologies.
Shinnosuke HAYAMIZU   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

R&D Activities of Flemish Companies in the Private Sector: An Analysis for the period 1998-2002 [PDF]

open access: yes
The second chapter of this Study analyses the results of the last two surveys (2000 and 2002). These surveys cover a period of rapid expansion of R&D-activities in the Flemish economy. The BERD has grown on average with nearly 13% yearly between 1998 and
Michele CINCERA
core  

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