Results 111 to 120 of about 56,943 (309)
The Determinants of Pharmaceutical R&D Expenditures: Evidence from Japan [PDF]
During the past 20 years, the world pharmaceutical industry has experienced a dramatic increase in R&D intensity. We apply and extend a model developed by Grabowski and Vernon (2000) with a pooled data sample of the 15 publicly listed Japanese drug firms
Roediger-Schluga, Thomas +1 more
core
R&D investment and financial contracting in spanish manufacturig firms [PDF]
, 2002 This paper presents a model in which a firm with a degree of R and D specialization raises external funds to develop a two-period project that involves some non-verifiable returns (R and D-type of project).
Martínez-Ros, Ester +3 more
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Impact of R&D Investment On Productivity - New Evidence Using Linked R&D-LRD Data [PDF]
This paper uses confidential Census longitudinal microdata to examine the association between R&D and productivity for the period 1972.1985. These data allow for significant improvements in measurement and model specification, yielding more precise ...
Donald Siegel, Frank R. Lichtenberg
core
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
In March 2000, the European Union’s Lisbon Agenda identified the low level of R&D as an important reason for Europe’s lacking economic growth. Seven years later, innovation still has the full attention of policy makers around Europe.
Sabine Visser
core
Job Creation Effects of R&D Expenditures: Are High-tech Sectors the Key?
, 2011 In this paper we assess the job creation effect of R&D expenditures, using a unique longitudinal database of 677 European companies over the period 1990-2008.
Bogliacino, Francesco +2 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
"Closing the R&D Gap, Evaluating the Sources of R&D Spending" [PDF]
Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can
Thomas Karier
core
Heart of Darkness: Modeling Public-Private Funding Interactions Inside the R&D Black Box [PDF]
This paper is a first step toward closing the analytical gap in the extensive literature on the results of interactions between public and private R&D expenditures, and their joint effects on the economy.
Bronwyn H. Hall, Paul A. David
core +2 more sources