Results 101 to 110 of about 56,943 (309)
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
R&D cooperation versus R&D subcontracting: empirical evidence from French survey data. [PDF]
This paper uses a survey of French firms active in R&D to identify the determinants of R&D outsourcing and of the ensuing trade-off between R&D subcontracting and R&D cooperation. Internal R&D expenditures increase both the probability of outsourcing and
Estelle Dhont-Peltrault, Etienne Pfister
core
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Patents and R and D at the Firm Level: A First Look [PDF]
This is a first report from a larger study of inventive activity of U.S. firms and some of its consequences. It reports on the relationship between patents applied for and R&D expenditures based on data for 121 large corporations covering the 1968-1975 ...
Zvi Griliches, Ariel Pakes
core
R&D tax credits, innovative activity and the targeting approach
Economics and Business ReviewThe aim of this study is to investigate whether the French R&D tax credit targeted at small and medium-sized enterprises (SMEs) has a positive impact on innovative activity. The French institutional setting provides a unique research framework as the R&D
Gjymshana Erik +2 more
doaj +1 more source
Total Factor Productivity and the R & D Expenditures
Statistika, 2009 The total factor productivity (TFP) growth comes from improvements in the quality of labor and capital and from other sources of technological change, many of them in the form of externalities, spillovers, representing contributions of science and innovations in other enterprises, industries and countries.
openaire +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Tax competitiveness and business R&D expenditures: do taxes matter for innovation?
Business, Management and Economics EngineeringPurpose – tax policies can be seen as one of the factors potentially affecting firms’ investment decisions and innovation. The paper examines the relationship between tax competitiveness and business Research and Development (R&D) expenditures across EU
Jan Hunady, Eleonora Demeova
doaj +1 more source
UK's net-zero carbon emissions target: Investigating the potential role of economic growth, financial development, and R&D expenditures based on historical data (1870-2017). [PDF]
Technol Forecast Soc Change, 2020 Shahbaz M +3 more
europepmc +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source