Results 131 to 140 of about 56,943 (309)

Quality of accounting information disclosure on technological R&D: comparative analysis of reports filed in Brazil and the United States by Brazilian companies

Revista Ambiente Contábil
Purpose: To analyze and compare the accounting information disclosure level on technological Research & Development (R&D) expenditures in accounting reports filed in Brazil and the United States by publicly traded Brazilian companies from different ...
Marco Aurélio Goulart Canongia, Adolfo Henrique Coutinho e Silva   +1 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Endogenous R&D Spillovers and Industrial Research Productivity [PDF]

This paper explores the implications of a simple model of learning and innovation by firms. In this model R&D spillovers are partly determined by firms, rather than by the given economic environment.
James D. Adams
core  

The impact of R&D expenditures on research performance on universities

, 2023
The most significant factor showing that countries are economically developed is the level of technology they produce. Technology, on the other hand, is the application of knowledge produced theoretically through scientific research. In this context, there is a clear connection between the level of economic development and welfare and the point reached
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A global dataset of public agricultural R&D investment: 1960-2022

Scientific Data
Investment in public agricultural R&D is a key driver of agricultural productivity, which is regarded as one of the major solutions to enhance global food security, reduce the environmental impact of agricultural production and enhance crop resilience to
Michiel van Dijk, Keith Fuglie, Paul W. Heisey, Haiyan Deng   +3 more
doaj   +1 more source

A firm-level dataset for analyzing entry, exit, employment and R&D expenditures in the UK: 1997-2012. [PDF]

Data Brief, 2016
Ugur M, Trushin E, Solomon E.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Productivity Growth and R&D Expenditure in Taiwan's Manufacturing Firms [PDF]

This study sets out to estimate the impact of R&D on productivity within the private sector, with further analysis of the different impacts of R&D in high-tech and conventional firms.
Kuen-Hung Tsai, Jiann-Chyuan Wang
core