Results 131 to 140 of about 5,017,645 (251)

SPATIAL-COMPETITION, INTEGRATED FRAMEWORK OF CENTRAL-PLACE SYSTEM WITH AGGLOMERATION ECONOMIES [PDF]

open access: yes
It is argued that the trade-off interaction between agglomeration economies and transportation costs cannot be excluded from the analysis of the central-place system.
Daisuke NAKAMURA
core  

The Influence of Profession, Experience and Geographical Region on Intra- and Postoperative Opioid Practice in Denmark: A Post Hoc Analysis of the OPIAID Survey. [PDF]

open access: yesActa Anaesthesiol Scand
Tran TXM   +8 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

MULTISCALAR CLUSTERS AND NETWORKS AS THE FOUNDATIONS OF INNOVATION DYNAMICS IN THE BIOPHARMACEUTICAL INDUSTRY [PDF]

open access: yes
Based on the case of the biopharmaceutical industry, the aim of this paper is to challenge the core conviction now widespread within the “spatial clustering theory”, which devotes a key (if not exclusive) role to geographical proximity in explaining ...
Abdelillah HAMDOUCH, Marc-Hubert DEPRET
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

MAPS OF CONTINUOUS SPATIAL DEPENDENCE [PDF]

open access: yes
Heterogeneity is one of the distinguishing features in spatial econometric models. It is a frequent problem in applied work and can be very damaging for statistical inference.
Ana ANGULO, Fernando LOPEZ, Jesús MUR
core  

A climate region classification for California's warm season: apparent temperature clustering to support heat-health epidemiology. [PDF]

open access: yesInt J Biometeorol
Villanueva M   +6 more
europepmc   +1 more source

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