Results 101 to 110 of about 112,087 (240)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Análisis regional de la pobreza para el colectivo de la Tercera Edad: inferencia clásica vs Técnicas Bootstrap [PDF]

open access: yes, 2010
En este trabajo se analiza el perfil regional de la pobreza en los hogares encabezados por mayores de 65 años, un colectivo especialmente sensible a situarse por debajo del umbral de pobreza. Para ello, a partir de los datos del fichero longitudinal de
Lucas Santos, Sonia de   +1 more
core   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

User interest-aware content replica optimized placement algorithm

open access: yesTongxin xuebao, 2014
A user interest-aware content replica optimized placement algorithm (UIARP) is proposed.Firstly,the interest subjects of the user-collective are extracted from their content access logs by clustering algorithms,and according to the weighting of the ...
Xiao-long YANG   +4 more
doaj   +2 more sources

Effect of disinfectant benzalkonium chloride on freshwater microalgae "Scenedesmus quadricauda" (Turpin) Brebisson [PDF]

open access: yes, 2015
[Resumen] El cloruro de benzalconio es utilizado frecuentemente como producto de limpieza y desinfección. Su uso intensivo puede provocar la contaminación de los medios acuáticos.
Ortún Capellán, Sofía
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Métrica y tensión dramática en la "Comedia de Bras Gil y Beringuella", de Lucas Fernández [PDF]

open access: yes, 2006
La crítica universitaria ha subrayado numerosas veces la herencia que la obra drámatica de Lucas Fernández debe a la lírica de cancionero, y en particular a las canciones dialogadas.
Coll Sansalvador, Andreu
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Toxicidad de antibióticos utilizados en acuicultura sobre una microalga marina [PDF]

open access: yes, 2014
Traballo fin de grao (UDC.CIE). Bioloxía.
Rodríguez López, Carlos María
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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