Results 111 to 120 of about 45,350 (227)
Deepfaked : propuesta de regulación de réplicas digitales
Fil: Mancini, Malena Beatriz. Universidad de San Andrés. Departamento de Derecho; Argentina.Las réplicas digitales o deepfakes son reproducciones virtuales de la imagen de una persona que aparentan ser reales.
Mancini, Malena Beatriz
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
, 2004 PROCESSO DE PRODUÇÃO E UTILIZAÇÃO DE ESPONJAS VEGETAIS DE FONTE RENOVAVEL PARA A OBTENÇÃO DE RÉPLICAS INORGÂNICAS DE MORFOLOGIA COMPLEXA DE CARBONATO DE CÁLCIO, HIDROXIAPATITA E ÓXIDO DE FERRO, RÉPLICAS INORGÂNICAS ASSIM OBTIDAS E SEUS RESPECTIVOS PÓS. A
Alves Oswaldo Luiz, Mazalli Italo Odone
core
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Investigação Experimental do Balanceamento de Réplicas no Sistema de Arquivos do Apache Hadoop
, 2019 International audienceO mecanismo de replicação de dados é a base para o funcionamento do HDFS, o sistema de arquivos do Apache Hadoop. Seguindo uma política de posicionamento, as réplicas são dispostas entre os nós do cluster, porém não há garantias de ...
Fazul, Rhauani, +1 more
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Etnográfica: Revista do Centro em Rede de Investigação em Antropologia, 2010 Este artigo pretende analisar os modos de desempenho das narrativas de viagem sobre a Índia, os significados que traduzem e transportam e o seu impacte ao nível das percepções e práticas discursivas no encontro do turismo internacional em Kolkata ...
Sandra C. S. Marques
doaj
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source