Results 101 to 110 of about 40,279 (236)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 2004 PROCESSO DE PRODUÇÃO E UTILIZAÇÃO DE ESPONJAS VEGETAIS DE FONTE RENOVAVEL PARA A OBTENÇÃO DE RÉPLICAS INORGÂNICAS DE MORFOLOGIA COMPLEXA DE CARBONATO DE CÁLCIO, HIDROXIAPATITA E ÓXIDO DE FERRO, RÉPLICAS INORGÂNICAS ASSIM OBTIDAS E SEUS RESPECTIVOS PÓS. A
Alves Oswaldo Luiz, Mazalli Italo Odone
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Deepfakes, réplicas digitais e o futuro do trabalho criativo: desafios e tendências regulatórias
This article analyzes the impact of deepfakes and digital replicas on the creative sector. It reflects on the creative sector\u27s concerns about the possible replacement of artists by avatars or synthetic characters, as well as the unauthorized use of ...
Azuaje Pirela, Michelle
core +1 more source
Fabricação e utilização experimentais de réplicas de tangas marajoara
, 2011 Apresentamos, neste trabalho, uma experimentação que envolveu a fabricação de várias réplicas de tangas marajoaras, assim como sua utilização por mulheres jovens.
Câmpera, Luiza +7 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Digital replicas and democracy: issues raised by the Hollywood actors’ strike
Humanities & Social Sciences CommunicationsRecent years have seen artificial intelligence (AI) technologies from large companies increasingly privatize people’s data, creating asymmetrical and undemocratic economic relations.
Asuka Yamazaki
doaj +1 more source