Results 71 to 80 of about 112,087 (240)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

De la investigación a la difusión: La experimentación como recurso didáctico en la elaboración de modelos de divulgación y puesta en valor del patrimonio arqueológico [PDF]

, 2012
La Didáctica que aborda aspectos arqueológicos, se ha revelado como una de las mejores herramientas para la comprensión del pasado, siendo en la actualidad un complemento imprescindible en museos, exposiciones temporales y puestas en valor de ...
Cuartero Monteagudo, Felipe, Martín Puig, Diego, Rubio Gil, Daniel, Sanmartí Esteban, Daniel   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Avaliação de um SGBD replicado usando simulação de redes [PDF]

, 2003
A replicação de sistemas de gestão de bases de dados (SGBD) é um mecanismo fundamental para a fiabilidade de sistemas de informação. Em sistemas geograficamente distribuídos é ainda útil na recuperação de desas- tres e disponibilidade ubíqua de dados ...
Correia, Alfrânio, Moura, Francisco Coelho Soares, Oliveira, Rui Carlos Mendes de, Pereira, José, Rocha, Luciano, Soares, L., Sousa, António   +6 more
core  

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Criação de um kit de fósseis do Paraná para inserção na Educação [PDF]

, 2017
Anais do 35º Seminário de Extensão Universitária da Região Sul - Área temática: EducaçãoNo âmbito do projeto de extensão Geodiversidade na Educação, em atividade na Universidade Estadual de Ponta Grossa (UEPG) desde 2011, vêm sendo concebidos materiais
Liccardo, Antonio, Lopes, Christopher Vinicius Santos, Mário Cézar   +1 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Replicas Strategy and Cache Optimization of Video Surveillance Systems Based on Cloud Storage

Future Internet, 2018
With the rapid development of video surveillance technology, especially the popularity of cloud-based video surveillance applications, video data begins to grow explosively. However, in the cloud-based video surveillance system, replicas occupy an amount
Rongheng Li, Jian Zhang, Wenfeng Shen
doaj   +1 more source

Escobajos de la vid como fuente de compuestos fenólicos con propiedades antioxidantes [PDF]

, 2019
Winemaking industry generates considerable amounts of bunch stems that are usually wasted despite their potential value as source of bioactive compounds. Phenolic profiles and antioxidant capacity (AC) of bunch stem extracts from eight grape varieties of
Bottini, Ambrosio Rubén, Ferreyra, Susana Gisela, Fontana, Ariel Ramón   +2 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source