Results 51 to 60 of about 281,757 (199)

La répression des prêtres réfractaires conduite hors de la loi sous la révolution française (1793 - an VIII)

open access: yesCahiers d'Études du Religieux- Recherches Interdisciplinaires, 2007
La période de la Révolution française fut marquée par une violente répression à l’encontre de l’Eglise catholique. C’est ainsi que les prêtres réfractaires furent poursuivis sur le fondement d’une procédure criminelle singulière : la mise hors de la loi.
Éric de Mari
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

1917 en Allemagne : mécontentement social et timidité politique ?

open access: yesCahiers d’histoire, 2017
L’agitation sociale en Allemagne peut apparaître paradoxale. Si la contestation politique ne s’exprime que de façon contenue au début de l’année 1917, l’insatisfaction des foules ouvrières face à l’effort imposé par la Première Guerre mondiale est ...
Alexandre Bibert
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

La répression anticommuniste du printemps 1940 au printemps 1941 : l’affaire de l’usine Breguet d’Aubervilliers

open access: yesCahiers d’histoire, 2019
L’arrestation des militants impliqués dans un réseau de distribution de tracts dans une usine métallurgique de la banlieue parisienne est exemplaire de la répression exercée au printemps 1940 contre un Parti communiste français réduit à la clandestinité ...
Louis Poulhès
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Du métro à la rue, de la désobéissance civile à la ‘Primera Línea’ : l’explosion sociale au Chili en octobre 2019

open access: yesAmnis
In October 2019, Chile is the scene of a social explosion that will deeply shake a country deemed stable. The purpose of this article is to study this unprecedented social mobilization since the end of the dictatorship through the relations between the ...
Nathalie Jammet-Arias
doaj   +1 more source

„Die Einheit von Kunst und Leben“ – eine totalitäre Utopie der politischen und künstlerischen Avantgarde. Die Kulturrevolution in der SU 1929 und der Bitterfelder Weg in der DDR 1959 im Vergleich

open access: yesILCEA, 2012
En publiant son programme de la « voie de Bitterfeld », dont le nom se rapporte au premier congrès de Bitterfeld en avril 1959 dans la Maison de la Culture de l’entreprise du peuple (= nationalisée) qui porte le nom de combinat électrotechnique de ...
Eckhard Gillen
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy