Results 81 to 90 of about 298,783 (242)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Dosage du plomb dans les vins, une cause d'enrichissement : les capsules de surbouchage

OENO One, 1977
Dans ce travail on décrit une technique de dosage du plomb par spectrophotométrie d'absorption atomique après extraction par la méthylisobutylcétone du plomb complexé avec la pyrrolidine dithiocarbamate d'ammonium et en utilisant la méthode des ajouts ...
Bernard Médina, Guy Guimberteau, P. Sudraud   +2 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

8 mars : contre la répression

, 1978
8 mars : contre la répression. In: Revue d'en face, n°3, 1978. pp.

core  

Milieux et mouvements libertaires pendant la Seconde République et la Guerre Civile espagnole

Diacronie. Studi di Storia Contemporanea, 2011
Anarchism is a political current that is distinguished by its diversity and heterogeneity. Yet, the libertarian circles have often been comprehended by historiography in a homogeneous way, contributing to reify their stories.
Arnaud Dolidier est doctorant à l’université Michel de Montaigne Bordeaux 3 avec une thèse intitulée : « Repartir à l’assaut du ciel ! Les mouvements libertaires durant la transition démocratique espagnole : ordre public et actions collectives (1975-1982) », sous la direction de M. François Godicheau. Domaine de recherche: histoire contemporaine de l’Espagne. Il a réalisé les Master 1 et Master 2 entre 2008 et 2010 sous la direction de M. Jean François Soulet et M. François Godicheau à l’université Toulouse 2 Le Mirail sur le thème : « La construction des identités collectives dans le milieu rural andalou pendant la Seconde République ». Il est membre de l’association « Adelante ».
doaj  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Règlementation communautaire des pratiques et traitements oenologiques

OENO One, 1978
Les nouveaux règlements communautaires concernant les pratiques et traitements œnologiques et les teneurs maximales en anhydride sulfureux total des vins entrant en vigueur le 1er septembre 1978 sont présentés et discutés en insistant sur les ...
P. Sudraud
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

La répression « ab irato »

, 1901
N. La répression « ab irato ». In: Manuel général de l'instruction primaire : journal hebdomadaire des instituteurs. 68e année, tome 37, 1901. pp.
N.
core  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source