Results 61 to 70 of about 402,700 (245)

La Traumatographie Hustonienne : De La Douleur Des Maux A La Couleur Des Mots

open access: yesRevue des Sciences Humaines, 2021
Une enfance traumatisante est pour certains, l’occasion de saisir sa plume  pour esquisser ses douleurs sur le blanc de la page et diluer la pesanteur des maux dans l’océan des mots.
Assia Birak, Tayeb Bouderbala
doaj  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Fonctionnalité, résilience, maintenance, acides gras insaturés Un exemple : l’acide linoléique et les récepteurs du LDL-cholestérol

open access: yesOléagineux, Corps gras, Lipides, 2001
Fonctionnalité, résilience, maintenance, et acides gras poly-insaturés. Il deviendra impossible dans le futur de poser le problème des apports nutritionnels conseillés sans se poser la question : Conseillés dans quel but ?
Mendy François
doaj   +1 more source

Vulnérabilité territoriale et résiliences: résistances et capacités adaptatives face aux aléas climatiques [PDF]

open access: yes, 2013
Namely inherited by its double "reactive" and "proactive" dimensioning, the multisacalar status of the resilience concept is illustrated here by the storm Xynthia, which occured in France on February 2010.
Quenault, Béatrice, woloszyn, philippe
core   +3 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Vulnérabilité territoriale et impacts climatiques dans le bassin du Mono (Togo)

open access: yesRevue Congolaise des Sciences et Technologies
Dans un contexte d’intensification des aléas climatiques avec des pluies extrêmes, sécheresses prolongées et feux de végétation, cette étude propose une analyse intégrée de la vulnérabilité des populations riveraines dans la partie septentrionale du ...
Ndigridema Narouwa   +9 more
doaj   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Arte, memoria y locura: vivencias como maestro en la escuela normal superior

open access: yesTrayectorias Humanas Trascontinentales, 2020
El artículo que a continuación se presenta, surge como producto de la labor realizada por el docente en la Escuela Normal Superior del municipio de Sonsón Antioquia. Este artículo atravesó por distintos momentos.
Wilton Alberto Zapata Muñoz
doaj   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund   +3 more
wiley   +1 more source

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