Results 31 to 40 of about 127,100 (203)
« On ne se libère pas du jour au lendemain du prêtre qu’on a dans la tête. »
Cahiers d’histoire, 2016 De 1965 à 1976, l’abbaye cistercienne de Boquen, située dans les Côtes d’Armor, abrite un projet communautaire original, la « Communion de Boquen ». Cette expérience, que l’on doit au très charismatique prieur du lieu, Bernard Besret, allie monachisme ...
Béatrice Lebel-Goascoz
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Sartre: a conferência de Araraquara
Trans/Form/Ação, 1988 Na conferência que pronunciou no Brasil, em Araraquara, Sartre, na linha direta de Questão de Método, retoma o tema - que a Resistência colocara na ordem do dia - das relações entre a teoria e a prática. Ora, cabe perguntar por que o autor, no umbral dos
Cristina Diniz Mendonça
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Mario Conde : Vie d’un Cubain à La Havane
Cahiers d’Études Romanes, 2006 Les récits policiers du romancier cubain Leonardo Padura (1955), dont la publication a commencé en 1991, constituent un authentique renouveau pour le roman policier cubain de la révolution.
Néstor Ponce
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FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
De la voix de son maître aux voix du peuple
Cahiers d’Études Romanes, 2015 L’invasion de l’Espagne en 1808 par les troupes napoléoniennes et l’accès au trône de Joseph Ier ne marquèrent pas seulement le début de ce que les Espagnols ont appelé la Guerre d’Indépendance.
Elisabel Larriba
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