Results 151 to 160 of about 21,646,526 (289)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Specialization, Factor Accumulation and Development [PDF]

open access: yes
The Heckscher-Ohlin theory links specialization of production to relative factor endowments. Endowments are the result of accumulation in response to economic in-centives. Taking this into account allows us to reconcile wildly di¤erent predictions in the
Doireann Fitzgerald, Juan Carlos Hallak
core  

Aladins Bayes Factor in R

open access: yes, 2017
Contains R scripts (created with https://www.r-project.org/) to calculate the Bayes Factor "a la Dienes". It also produces plots (inspired by JASP, https://jasp-stats.org/). Please cite as follows: Wiens, S. (2017). Aladins Bayes Factor in R.
Stefan Wiens
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Control of expression of the I factor, a LINE-like transposable element in Drosophila melanogaster [PDF]

open access: yes, 1996
I factors are LINE-like transposable elements in the genome of Drosophila melanogaster. They normally transpose infrequently but are activated in the germline of female progeny of crosses between males of a strain that contains complete elements, an I or
Finnegan, D J   +4 more
core  

Validation of an instrument for understanding school absence: the Swedish version of the adapted school refusal assessment scale-revised

open access: yesBMC Psychology
Background The School Refusal Assessment Scale-Revised (SRAS-R) is a widely used measure to understand school attendance problems. However, previous evaluations have yielded inconsistent findings on the factor structure.
Johan Strömbeck   +3 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Power Factor

open access: yes
All About Circuits is a website that âprovides a series of online textbooks covering electricity and electronics.â Written by Tony R. Kuphaldt, the textbooks available here are wonderful resources for students, teachers, and anyone who is interested in ...
Kuphaldt, Tony R.
core  

ENDURANCE EXERCISE TRAINING AND DIFERULOYL METHANE SUPPLEMENT: CHANGES IN NEUROTROPHIC FACTOR AND OXIDATIVE STRESS INDUCED BY LEAD IN RAT BRAIN

open access: yesBiology of Sport, 2013
For many years it has been known that lead is life-threatening, not only as an air pollutant but also because of it has been associated with several conditions including degenerative disease of the nervous system.
Valiollah Dabidi Roshan   +4 more
doaj  

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