Results 91 to 100 of about 3,517,480 (298)

An “Amyloid‐β Cleaner” for the Treatment of Alzheimer's Disease by Normalizing Microglial Dysfunction

Advanced Science, 2020
Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by progressive cognitive and memory loss. The vicious circle between dysfunctional microglia and amyloid‐β (Aβ) is a crucial pathological event and accelerates the ...
Ruiyuan Liu, Jun Yang, Linying Liu, Zhiguo Lu, Zhuyan Shi, Weihong Ji, Jie Shen, Xin Zhang   +7 more
doaj   +1 more source

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

The Hamburg/ESO R-process Enhanced Star survey (HERES). V. Detailed abundance analysis of the r-process enhanced star HE 2327-5642

, 2010
We report on a detailed abundance analysis of the strongly r-process enhanced giant star, HE 2327-5642 ([Fe/H] = -2.78, [r/Fe] = +0.99). Determination of stellar parameters and element abundances was based on analysis of high-quality VLT/UVES spectra ...
A. Velichko, Andrievsky, Anstee, Aoki, Arlandini, Asplund, Bard, Barklem, Barklem, Barklem, Barklem, Barklem, Barklem, Baumüller, Beers, Beers, Belyakova, Bergemann, Bergemann, Bizzarri, Biémont, Biémont, Blackwell, Booth, Bord, Borghs, Cardon, Cayrel, Cayrel, Christlieb, Christlieb, Cowan, Cowan, Den Hartog, Den Hartog, Farouqi, Farouqi, François, Frebel, Freiburghaus, Fuhrmann, Gehren, Ginibre, Gustafsson, Hannaford, Hayek, Heiter, Hill, Holt, Honda, Honda, Honda, Huber, Iben, Ivans, Ivarsson, Ivarsson, Johnson, Jonsell, Kling, Kupka, Kurucz, L. Mashonkina, Lai, Lawler, Lawler, Lawler, Lawler, Lawler, Lawler, Lawler, Lawler, Lawler, Lawler, Lefébvre, Lind, Ljung, Lodders, Malcheva, Mashonkina, Mashonkina, Mashonkina, Mashonkina, Mashonkina, Mashonkina, Mashonkina, McWilliam, McWilliam, Meléndez, Mårtensson-Pendrill, N. Christlieb, Nilsson, Nitz, Nörtershäuser, O'Brian, O'Brian, P. S. Barklem, Pickering, Pickering, Plez, Qian, Qian, Roederer, Roederer, Sakhibullin, Sansonetti, Schlegel, Shi, Smith, Smith, Smith, Sneden, Sneden, Sneden, Sneden, Sneden, Spergel, Spite, Steenbock, T. C. Beers, Takahashi, Takeda, Theodosiou, Travaglio, Travaglio, Truran, Truran, V. Hill, Vidal, Vidal, Wickliffe, Wiese, Woosley, Woosley, Xu, Zhang, Zhao   +136 more
core   +3 more sources

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

The r-Process in Supersonic Neutrino-Driven Winds: The Roll of Wind Termination Shock

, 2007
Recent hydrodynamic studies of core-collapse supernovae imply that the neutrino-heated ejecta from a nascent neutron star develops to supersonic outflows.
Akira Ohnishi, Ken'ichi Nomoto, Kiyoshi Kato, Masayuki Y. Fujimoto, Shigeru Kubono, Shinya Wanajo, Takami Kuroda, Takaya Nozawa, Takuma Suda, Toshitaka Kajino   +9 more
core   +1 more source

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles, Greg Russell, Leila H. DeWitt, Kimberly Montez, Callie L. Brown   +4 more
wiley   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

A Simple Model for r-Process Scatter and Halo Evolution

, 2001
Recent observations of heavy elements produced by rapid neutron capture (r-process) in the halo have shown a striking and unexpected behavior: within a single star, the relative abundances of r-process elements heavier than Eu are the same as the same as
Argast D., Brian D. Fields, Edvardsson B., James W. Truran, Jehin E., John J. Cowan, Rosswog S., Truran J. W., Wasserburg G. J.   +8 more
core   +2 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Sensitivity studies for r-process nucleosynthesis in three astrophysical scenarios

, 2013
In rapid neutron capture, or r-process, nucleosynthesis, heavy elements are built up via a sequence of neutron captures and beta decays that involves thousands of nuclei far from stability.
Aprahamian, A., Bentley, I., Cass, J., McLaughlin, G. C., Mumpower, M., Surman, R.   +5 more
core   +2 more sources