Results 161 to 170 of about 3,422,985 (329)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Evidence for supernova injection into the solar nebula and the decoupling of r-process nucleosynthesis. [PDF]
Proc Natl Acad Sci U S A, 2013 Brennecka GA, Borg LE, Wadhwa M.
europepmc +1 more source
Expected Limits on R-symmetric $\mu \to e $ Processes at Project X [PDF]
, 2012 Ricky Fok
openalex +1 more source
Proposed Lunar Measurements of $r$-Process Radioisotopes to Distinguish Origin of Deep-sea 244Pu [PDF]
, 2021 Xilu Wang +8 more
openalex +1 more source
The r-process nucleosynthesis: Nuclear physics challenges
AIP Conference Proceedings, 2012 About half of the nuclei heavier than iron observed in nature are produced by the socalled rapid neutron capture process, or r-process, of nucleosynthesis. The identification of the astrophysics site and the specific conditions in which the r-process takes place remains, however, one of the still-unsolved mysteries of modern astrophysics.
openaire +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Recent Advances in Understanding R-Process Nucleosynthesis in Metal-Poor Stars and Stellar Systems
UniverseThe rapid neutron-capture process (r-process) is responsible for the creation of roughly half of the elements heavier than iron, including precious metals like silver, gold, and platinum, as well as radioactive elements such as thorium and uranium ...
Avrajit Bandyopadhyay, Timothy C. Beers
doaj +1 more source
Astronomy & AstrophysicsThe astrophysical origin of the rapid neutron-capture process (r-process), responsible for producing roughly half of the elements heavier than iron, remains uncertain. Detailed chemical signatures from the oldest, most metal-poor stars, which act as fossil records of the earliest nucleosynthesis events, can be used to identify the dominant r-process ...
Racca, Mila +13 more
openaire +2 more sources