Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Arf6 is recruited by R. typhi RalF and is required for infection.
(A) Ectopically expressed RalFRtFL co-localizes with Arf6 but not Arf5. HeLa cells co-expressing EYFP, EYFP-RalFRtFL or EYFP-RalFRbFL and mRFP-Arf6 (left) or -Arf5 (right) were fixed with 4% para-formaldehyde. Nuclei were stained with DAPI (blue). (Scale
M. Sayeedur Rahman (24644) +7 more
core +1 more source
Rickettsia typhi en roedores de una comunidad con antecedentes de tifo murino, de Yucatán, México.
Objective. To determine the presence of Rickettsia typhi in synanthropic rodents captured in the rural community of Bolmay, Yucatan, Mexico, an area with history of murine typhus cases. Materials and methods.
Martínez-Ortiz, Daly +8 more
core +2 more sources
Improved Detection and Sequencing of Rickettsia spp. DNA in South African Wildlife
Nested gltA PCR detected Rickettsia spp. DNA in 44% of South African wildlife samples previously negative by RLB, revealing spotted fever, typhus and transitional group lineages, novel host records, co‐infection and multi‐organ dissemination in impala, highlighting complex wildlife involvement and zoonotic risk within a One Health framework.
Carlo Andrea Cossu +5 more
wiley +1 more source
Murine Typhus and Leptospirosis as Causes of Acute Undifferentiated Fever, Indonesia [PDF]
To investigate rickettsioses and leptospirosis among urban residents of Semarang, Indonesia, we tested the blood of 137 patients with fever. Evidence of Rickettsia typhi, the agent of murine typhus, was found in 9 patients.
Hartskeerl, Rudy A. +5 more
core
Salmonella typhi is a bacteria that leads to typhoid fever and one of the causes of death due to bacteria infections. In Indonesia, typhoid fever occurs around 1,100 cases per 100,000 population per year, with a mortality rate of 3.1-10.4%.
Muktiningsih Nurjayadi +19 more
doaj +1 more source
MΦ hardly respond to R. typhi and are uncapable to kill the bacteria.
To analyze a correlation of bacterial uptake and activation status of CD11b+GR1low MΦ /monocytes and CD11b+GR1hi neutrophils in vivo the respective cell population in the spleen and liver of the mice described in Fig 5 was first gated on iNOS+ cells and ...
Jessica Rauch (3070527) +8 more
core +1 more source
Background: Typhoid fever is an acute infection caused by the bacteria Salmonella typhi. In typhoid fever patients, abnormal leukocyte, lymphocyte, and neutrophil counts are often found. Typhoid fever is prevalent in tropical regions, including Indonesia,
Desi Fitriani, Andika Aliviameita
doaj +1 more source
Analysis of Rickettsia typhi ‐infected and uninfected cat flea ( Ctenocephalides felis ) midgut cDNA libraries: deciphering molecular pathways involved in host response to R. typhi infection [PDF]
Abstract Murine typhus is a flea‐borne febrile illness that is caused by the obligate intracellular bacterium, Rickettsia typhi . The cat flea, Ctenocephalides felis , acquires R.
S. M. Dreher‐Lesnick +7 more
openaire +1 more source
ABSTRACT In this study, a unique pH‐sensitive PEG/C/PVA hydrogel based on chitosan (C), polyvinyl propylene (PVP) and polyethylenglycol (PEG) crosslinked with tetraethyl orthosilicate (TEOS) was fabricated. This PEG/C/PVA hydrogel was designed to deliver different drugs with distinct release profiles, including diclofenac sodium and ciprofloxacin, and ...
Danial Mazhar +4 more
wiley +1 more source

