Results 81 to 90 of about 1,105,597 (253)

Real‐World Experience With Multimodal Treatment of Resectable Stage II–III Non‐Small Cell Lung Cancer: A Single Institutional Analysis

International Journal of Cancer, EarlyView.
ABSTRACT Neoadjuvant therapy has recently become an integral component of multimodal treatment for resectable lung cancer. However, real‐world data on perioperative morbidity and treatment adherence remain limited. This study aimed to assess the feasibility and safety of different neoadjuvant treatment approaches applied within daily clinical routine ...
Raffaella Griffo, Benedikt Niedermaier, Laura V. Klotz, Marc Schneider, Michael Allgäuer, Marc Kriegsmann, Romina M. Roesch, Lena Brendel, Henrike Deissner, Farastuk Bozorgmehr, Petros Christopoulos, Michael Thomas, Hauke Winter, Martin E. Eichhorn, Florian Eichhorn   +14 more
wiley   +1 more source

Image3_TRAIL-R1-Targeted CAR-T Cells Exhibit Dual Antitumor Efficacy.jpg

, 2021
Tumor necrosis factor–related apoptosis-inducing ligand receptor 1 (TRAIL-R1) has limited expression in normal tissues but was highly expressed in various types of tumors, making it an attractive target for cancer immunotherapy.
Wang Wang (262236), Jingjing Huang (170112), Xiaojian Han (10338653), Aishun Jin (107723), Meiying Shen (10338656), Tingting Li (10553), Yaru Nai (10338674), Li Du (397426), Feiyang Luo (10338665), Da Pang (110728)   +9 more
core   +1 more source

Routine MDM2 FISH Testing and Preoperative Biopsy Reduces Recurrence Rate of Atypical Lipomatous Tumours

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Although MDM2 FISH test has been increasingly used to differentiate ALT and benign lipomatous tumours, its impact on clinical outcome remains underexplored. This study investigated whether routine MDM2 FISH testing on preoperative biopsy is associated with a reduction in the recurrence risk of ALT.
Samuel O. H. Ching, Anderson S. M. Leung, Raymond C. H. Yau, Albert Y. L. Lam, Tony W. H. Shek, Maximus C. F. Yeung   +5 more
wiley   +1 more source

Impact of resection margin on outcome in soft-tissue sarcomas of the extremities treated with limb-sparing surgery and postoperative radiotherapy

World Journal of Surgical Oncology
Background The standard curative treatments for extremity soft tissue sarcoma (ESTS) include surgical resection with negative margins and perioperative radiotherapy. However, the optimal resection margin remains controversial.
Chun-Chieh Chen, Yao-Yu Wu, Jo-Ting Kao, Chih‑Hsiang Chang, Shih-Chiang Huang, Hsin‑Nung Shih   +5 more
doaj   +1 more source

Imaging memory in temporal lobe epilepsy: predicting the effects of temporal lobe resection [PDF]

, 2010
Functional magnetic resonance imaging can demonstrate the functional anatomy of cognitive processes. In patients with refractory temporal lobe epilepsy, evaluation of preoperative verbal and visual memory function is important as anterior temporal lobe ...
Thompson, P. J., Samson, R. S., Yogarajah, M., Symms, M. R., Koepp, M. J., Powell, R. H. W., Duncan, J. S., Bonelli, S. B.   +7 more
core  

What management for patients with R1 resection after total mesorectal excision for rectal cancer? A review of the literature

, 2022
International audienceAim of the study: Treatment for rectal cancer is very standardized. However, for total mesorectal excision (TME) with positive margins at microscopic pathological examination (classified R1 ), there is no consensus regarding ...
Theuil, L., Bertrand, M.M., Prudhomme, M.   +2 more
core   +1 more source

Prognostic Determinants of Overall Survival After Resection for Pancreatic Ductal Adenocarcinoma: A Consensus‐Based Conceptual Framework

Journal of Surgical Oncology, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis despite surgical resection, yet the prognostic literature remains fragmented across hundreds of single‐institution studies that vary in design, covariates, and analytical approaches.
Muhammad Maisam Ali, Kaleem S. Ahmed, Clayton T. Marcinak, Syed Ali Tayyeb Hasan, Anne D. Letocha, Noorain Ahmad, Haider bin Khalid, Kainat Fatima, Syed Nabeel Zafar   +8 more
wiley   +1 more source

Clinical Applications of 3D Specimen Scanning and Margin Mapping in Musculoskeletal Oncology: A 36 Patient Case Series

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Text‐based pathology reports inadequately communicate complex three‐dimensional (3D) relationships in musculoskeletal oncology, potentially contributing to errors in re‐resection and adjuvant treatment planning. While our prior 7‐case pilot study established technical feasibility, the scalability of this workflow and its utility as ...
Riley S. Gilbertson, Sakshi Krishna, Joaquin Austerlitz, Andreja Radevic, Michael J. Colello, Alexander N. Perez, Reena Singh, Jennifer L. Halpern, Herbert S. Schwartz, Michael C. Topf, Joshua M. Lawrenz, Daniel J. Johnson   +11 more
wiley   +1 more source

Impact of histological and clinical parameters on resection status and recurrence probability in head and neck basal cell carcinomas

Frontiers in Oncology
ObjectivesThis study aims to identify histological and clinical parameters associated with an R1 resection status and the recurrence rate in surgically treated basal cell carcinomas (BCC) and to evaluate the impact of an initial R1 resection status on ...
Felix Deffner, Givi Magradze, Kia Melzer, Anna Charlotta Schlieper, Andreas Knopf, Naglaa Mansour, Christoph Becker, Manuel Christoph Ketterer   +7 more
doaj   +1 more source

The impact of postoperative transcatheter arterial infusion and systemic adjuvant therapy on prognosis in patients with R1 resection for hilar cholangiocarcinoma [PDF]

Yixue xinzhi zazhi
Objective Exploring the impact of postoperative transarterial infusion (TAI) and systemic adjuvant therapy on the prognosis of patients with hilar cholangiocarcinoma (HCCA) who have undergone R1 resection.Methods Retrospectively analyze the clinical data
GENG Qin, QIAN Chunxing, LI Guowang, KANG Qiang, KE Yang, LI Jing, YANG Chen, LI Yuehua   +7 more
doaj   +1 more source