Results 71 to 80 of about 1,105,597 (253)
ABSTRACT Background Postoperative radiotherapy is the standard treatment for locally advanced oral squamous cell carcinoma (OSCC); however, the indication for neck irradiation (NI) in pN0 patients remains debatable. We evaluated whether the omission of NI compromises outcomes in pT3–T4 pN0 patients treated with adequate neck dissection (ND).
Mathilde Mirallié +9 more
wiley +1 more source
ABSTRACT Background Locoregional recurrence remains a clinically relevant problem in oral squamous cell carcinoma (OSCC). Whether local, ipsilateral nodal, and contralateral nodal failure represent distinct disease processes with different clinicopathological associations has not been systematically evaluated.
Jannik Ketschau +9 more
wiley +1 more source
Incomplete resection (R1) and local recurrence of colorectal cancer continue to be a significant surgical problem. Radical resection of bowel and lymph node bassin are clearly necessary after incomplete endoscopic resection or local surgical excision ...
Schlag, P.M., Huenerbein, M.
core +1 more source
ABSTRACT Background Perineural invasion (PNI) is an established adverse prognostic factor in oral squamous cell carcinoma (OSCC), but the implications of its extent as well as its relationship with surgical margin status and the extent of microscopic tumor spread remain unclear.
Michael A. Müller +7 more
wiley +1 more source
Survival and prognostic factors in conventional central chondrosarcoma
Background Chondrosarcoma is the second most frequent primary malignant bone tumor. Treatment is mainly based on surgery. In general, wide resection is advocated at least in G2 and G3 tumors. But which margins should be achieved? Does localization as for
Julian Fromm +8 more
doaj +1 more source
Prognostic factors affecting overall survival in R0 and R1 resection by multivariate analysis.
Prognostic factors affecting overall survival in R0 and R1 resection by multivariate analysis.
Ji Kon Ryu (481706) +8 more
core +1 more source
Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue +6 more
wiley +1 more source
Severe Postoperative Complications Adversely Affect Long-Term Survival After R1 Resection for Pancreatic Head Adenocarcinoma [PDF]
Background: Survival after pancreatic head adenocarcinoma surgery is determined by tumor characteristics, resection margins, and adjuvant chemotherapy. Few studies have analyzed the long-term impact of postoperative morbidity.
Demartines, Nicolas +2 more
core
Prognostic factors affecting disease-free survival in R0 and R1 resection by multivariate analysis.
Prognostic factors affecting disease-free survival in R0 and R1 resection by multivariate analysis.
Ji Kon Ryu (481706) +8 more
core +1 more source
Image1_TRAIL-R1-Targeted CAR-T Cells Exhibit Dual Antitumor Efficacy.jpg
Tumor necrosis factor–related apoptosis-inducing ligand receptor 1 (TRAIL-R1) has limited expression in normal tissues but was highly expressed in various types of tumors, making it an attractive target for cancer immunotherapy.
Wang Wang (262236) +9 more
core +1 more source

