Results 71 to 80 of about 1,105,597 (253)

Safe Omission of Postoperative Neck Irradiation in Selected pN0 Patients With Locally Advanced Oral Cavity Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Postoperative radiotherapy is the standard treatment for locally advanced oral squamous cell carcinoma (OSCC); however, the indication for neck irradiation (NI) in pN0 patients remains debatable. We evaluated whether the omission of NI compromises outcomes in pT3–T4 pN0 patients treated with adequate neck dissection (ND).
Mathilde Mirallié   +9 more
wiley   +1 more source

From Nodal Metastasis to Oncologic Recurrence in Tongue and Oral Floor Squamous Cell Carcinoma: Distinct Failure Patterns and Clinicopathological Risk Profiles

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Locoregional recurrence remains a clinically relevant problem in oral squamous cell carcinoma (OSCC). Whether local, ipsilateral nodal, and contralateral nodal failure represent distinct disease processes with different clinicopathological associations has not been systematically evaluated.
Jannik Ketschau   +9 more
wiley   +1 more source

[R1 resection in the region of the lower gastrointestinal tract: relevance and therapeutic consequences]

open access: yes, 2007
Incomplete resection (R1) and local recurrence of colorectal cancer continue to be a significant surgical problem. Radical resection of bowel and lymph node bassin are clearly necessary after incomplete endoscopic resection or local surgical excision ...
Schlag, P.M., Huenerbein, M.
core   +1 more source

Characterization of Perineural Invasion Parameters for Risk Stratification in Oral Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Perineural invasion (PNI) is an established adverse prognostic factor in oral squamous cell carcinoma (OSCC), but the implications of its extent as well as its relationship with surgical margin status and the extent of microscopic tumor spread remain unclear.
Michael A. Müller   +7 more
wiley   +1 more source

Survival and prognostic factors in conventional central chondrosarcoma

open access: yesBMC Cancer, 2018
Background Chondrosarcoma is the second most frequent primary malignant bone tumor. Treatment is mainly based on surgery. In general, wide resection is advocated at least in G2 and G3 tumors. But which margins should be achieved? Does localization as for
Julian Fromm   +8 more
doaj   +1 more source

Prognostic factors affecting overall survival in R0 and R1 resection by multivariate analysis.

open access: yes, 2013
Prognostic factors affecting overall survival in R0 and R1 resection by multivariate analysis.
Ji Kon Ryu (481706)   +8 more
core   +1 more source

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue   +6 more
wiley   +1 more source

Severe Postoperative Complications Adversely Affect Long-Term Survival After R1 Resection for Pancreatic Head Adenocarcinoma [PDF]

open access: yes, 2018
Background: Survival after pancreatic head adenocarcinoma surgery is determined by tumor characteristics, resection margins, and adjuvant chemotherapy. Few studies have analyzed the long-term impact of postoperative morbidity.
Demartines, Nicolas   +2 more
core  

Prognostic factors affecting disease-free survival in R0 and R1 resection by multivariate analysis.

open access: yes, 2013
Prognostic factors affecting disease-free survival in R0 and R1 resection by multivariate analysis.
Ji Kon Ryu (481706)   +8 more
core   +1 more source

Image1_TRAIL-R1-Targeted CAR-T Cells Exhibit Dual Antitumor Efficacy.jpg

open access: yes, 2021
Tumor necrosis factor–related apoptosis-inducing ligand receptor 1 (TRAIL-R1) has limited expression in normal tissues but was highly expressed in various types of tumors, making it an attractive target for cancer immunotherapy.
Wang Wang (262236)   +9 more
core   +1 more source

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