Gene List Selection Matters: Missed Diagnoses in Prenatal Exome Sequencing—PanelApp R21 and HPO‐Driven Versus OMIM‐Based Gene Lists [PDF]
Prenatal Diagnosis, EarlyView.ABSTRACT Objective To evaluate whether the causative variants found upon clinical exome sequencing in fetuses affected with selected structural anomalies would also be detected if PanelApp‐R21 or Human Phenotype Ontology (HPO)‐driven gene selection terms were applied instead.
Victoria Ardiles‐Ruesjas +7 more
openalex +2 more sources
The role of R21 expression in differential diagnosis of melanocytic lesions
Indian Journal of Pathology and Microbiology, 2023 Background: Cyclic adenosine monophosphate (cAMP) is an intracellular signal transmitter involved in the regulation of melanocyte growth, proliferation, and melanogenesis.
Didem Turcan +2 more
doaj +1 more source
Housing Tenure Preferences among Students from Two Polish Universities
Real Estate Management and Valuation, 2021 The housing rental market in Poland is underdeveloped and tilted towards temporary tenants, usually students and immigrants. To explore the flaws in the functioning of this market, we conduct a survey among 315 students from two Polish universities.
Rubaszek Michał, Rubaszek Justyna
doaj +1 more source
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Hepatology, EarlyView., 2022 EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
Absorption Rate as a Tool for Assessing the Dynamics of Development Activity
Folia Oeconomica Stetinensia, 2021 Research background: An assessment of the dynamics of the development of the housing market is critical for development activity and the institutions that finance it.
Antczak-Stępniak Agata
doaj +1 more source
Forensic Science International: Reports, 2021 South African cannabis based products that were submitted to a private laboratory for the determination of heavy metal residues, were analysed. Two USP 232/ICH Q3D (United States Pharmacopoeia (USP), 2016; Elder and Teasdale, 2014) [2] specifications ...
Hendrik Jacobus Viviers +2 more
doaj +1 more source
Psychodynamic therapy: a poorly defined concept with questionable evidence [PDF]
, 2016 R34 MH086668 - NIMH NIH HHS; R01 AT007257 - NCCIH NIH HHS; R21 MH101567 - NIMH NIH HHS; R34 MH099311 - NIMH NIH HHS; R21 MH102646 - NIMH NIH HHS; K23 MH100259 - NIMH NIH HHS; R01 MH099021 - NIMH NIH ...
Hofmann, Stefan G.
core +1 more source
Interpersonal Emotion Regulation Questionnaire (IERQ): scale development and psychometric characteristics [PDF]
, 2016 Despite the popularity of emotion regulation in the contemporary literature, research has almost exclusively focused on only intrapersonal processes, whereas much less attention has been placed in interpersonal emotion regulation processes.
Carpenter, Joseph K. +2 more
core +1 more source
Scientific Reports, 2021 An effective vaccine would be a valuable tool for malaria control and elimination; however, the leading malaria vaccine in development, RTS,S/AS01, provided only partial protection in a Phase 3 trial. R21 is a next-generation RTS,S-like vaccine.
Katharine A. Collins +10 more
doaj +1 more source
Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities [PDF]
, 2014 SIRT1, a class III histone deacetylase, plays a critical role in regulating cancer cell growth, migration and invasion, which makes it a potential target for cancer therapeutics.
Chiao, Christine Ya-Chi +6 more
core +2 more sources