A stepwise emergence of evolution in the RNA world
FEBS Letters, Volume 599, Issue 19, Page 2706-2717, October 2025.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
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