Results 11 to 20 of about 1,668 (148)

Genetic Differentiation in the SdhC Subunit Confers Intrinsic Resistance to SDHI Fungicides in Fusarium asiaticum. [PDF]

Mol Plant Pathol
In Fusarium asiaticum, two homologous SdhC subunits (FaSdhC1/C2) regulate sensitivity to SDHI fungicides: deletion of FaSDHC1 decreases sensitivity, while deletion of FaSDHC2 increases it. Multiple mutations in ΔFaSDHC2 confer resistance to SDHI fungicides.
Song J, Wang J, Liu X, Liu Y, Bi L, Li M, Cai Y, Zhou M, Duan Y.   +8 more
europepmc   +2 more sources

Testosterone modulates multispectral oscillatory activity serving performance of motor sequences in typically developing youth. [PDF]

J Physiol
Abstract figure legend Increases in testosterone are associated with developmental changes in motor‐related neural oscillations in youth. Abstract Motor control is critical to daily functioning and undergoes significant refinement throughout youth. Although the effects of age on the underlying brain circuitry have been well characterized, fewer studies
Derby J, Ward TW, Petro NM, Son JJ, Ende GC, Rice DL, Coutant AT, Steiner EL, Calhoun VD, Wang YP, Stephen JM, Heinrichs-Graham E, Wilson TW.   +12 more
europepmc   +2 more sources

CD38 symmetric dimethyl site R58 promotes malignant tumor cell immune escape by regulating the cAMP-GSK3β-PD-L1 axis. [PDF]

Heliyon
In recent years, immunotherapy has emerged as an effective approach for treating tumors, with programmed cell death ligand 1 (PD-L1)/programmed cell death protein-1 (PD-1) immune checkpoint blockade (ICB) being a promising strategy. However, suboptimal therapeutic efficacy limits its clinical benefit.
Liang L, Yue C, Li W, Tang J, He Q, Zeng F, Cao J, Liu S, Chen Y, Li X, Zhou Y.   +10 more
europepmc   +4 more sources

AcrVA3 Is a Double Strand DNA-Cleaving Anti-CRISPR That Indirectly Inhibits Cas12. [PDF]

FASEB J
This study reports the high‐resolution structure of the anti‐CRISPR protein AcrVA3 and reveals its unexpected inhibitory mechanism against Cas12. AcrVA3 does not directly interact with Cas12 but instead exhibits double‐stranded DNA cleavage activity.
Han JH, Kang YJ, Lee SY, Jin HB, Lee CS, Park HH.   +5 more
europepmc   +2 more sources

Doppler imaging and surface differential rotation of young open cluster stars - I. HD 307938 (R58) in IC 2602 [PDF]

Monthly Notices of the Royal Astronomical Society, 2005
ISSN:0035 ...
Stephen Marsden, Bradley Carter, I A Waite   +2 more
exaly   +4 more sources

Intravascular Lithotripsy Is Associated With Superior Clinical Outcomes Compared to Atherectomy: A Large-Scale, Propensity-Matched Analysis. [PDF]

Catheter Cardiovasc Interv
ABSTRACT Background Coronary artery disease (CAD) with severe calcification remains a growing challenge in percutaneous coronary intervention (PCI). Atherectomy (ATH) has long been used for plaque modification, whereas intravascular lithotripsy (IVL) has emerged as a promising alternative. Large‐scale comparative data on long‐term outcomes are limited.
Miks CD, Ozaki GK, Shukla CR, Sharma V.
europepmc   +2 more sources

Clinical and Genetic Landscape of Glioblastoma, IDH-Wildtype With FGFR Gene Family Alterations. [PDF]

Cancer Sci
We analyzed 1076 cases of glioblastoma, IDH‐wildtype (GBM, IDH‐wt) using the C‐CAT genomic database to clarify the clinical and genetic features of FGFR alterations. FGFR::TACC fusions and FGFR1 mutations were identified in distinct subsets and were associated with unique co‐mutation patterns.
Kegoya Y, Otani Y, Mizuta R, Ikemachi R, Kamiura M, Ishida J, Toyooka S, Ennishi D, Tomida S, Tanaka S.   +9 more
europepmc   +2 more sources

R58. Ps. Arnaldus de Vilanova / Nicolaus Comes (Nicolaus de Comitibus)?/ Iohannes de Thesen? [PDF]

, 2007
C Cardelle De Hartmann
exaly   +5 more sources

Design and optimization of a semi-trailer extendable RUPD according to UNECE R58

Engineering Perspective, 2022
Extensive tests was carried out on the rear protection equipment of a tipper-type silobus semi-trailer. This study includes the design and optimization process of an extensible rear underrun protective device for O4 category semi-trailers. Material selection and structural design features were evaluated within the framework of harmonization with ...
Fakı Binboğa, Ebubekir Hubeyb Şimşek
openaire   +2 more sources

Changes in the core-Periphery Structure of the Framework Programme’s Regional Network

Studia Ekonomiczne i Regionalne, 2023
The aim of this paper is to measure whether the regions lagging behind in the European knowledge field could get closer to the core of the Framework Programmes’ (FP) R&D network.
Bilicz Dávid
doaj   +1 more source