Results 51 to 60 of about 2,402 (172)

Primary results of matched cohort analyses on acute hospital mortality versus PROWESS at 28 days

, 2011
PROWESS, Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.Copyright information:Taken from "Drotrecogin alfa (activated): real-life use and outcomes for the UK"http://ccforum.com/content/12/2/R58Critical Care 2008;12(2):R58-R58.
Kathryn M Rowan (94205), David A Harrison (3740), Emma North (94206), Catherine A Welch (64955)   +3 more
core   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

An Equatorial Hemispheric Barrier Shapes the Diversification of Migratory Belenois Butterflies

Molecular Ecology, Volume 35, Issue 6, March 2026.
ABSTRACT Biogeographic barriers are typically considered prominent geographic features that block or severely restrict dispersal and gene flow. However, mating barriers can also emerge within continuous suitable habitats, driven by ecological or behavioural constraints. Migratory insects show an extraordinary capacity to traverse vast geographic ranges,
Anna Janiczek, Aleix Palahí, Leonardo Dapporto, Gemma Díaz‐Martínez, Vazrick Nazari, Aurora García‐Berro, Farid Bahleman, Steve C. Collins, Perpetra Akite, Michael F. Braby, Niclas Backström, Roger Vila, Tomasz Suchan, Gerard Talavera   +13 more
wiley   +1 more source

Subgroup results: acute hospital mortality for individual matching to control pool 4

, 2011
Pool 4 includes patients from a contemporaneous drotrecogin alfa (activated; DrotAA) unit but before the first use in that unit.Copyright information:Taken from "Drotrecogin alfa (activated): real-life use and outcomes for the UK"http://ccforum.com ...
Kathryn M Rowan (94205), David A Harrison (3740), Emma North (94206), Catherine A Welch (64955)   +3 more
core   +1 more source

Patterns of Interploidy Admixture in Polyploid Complexes: Insights From Thymus Sect. Mastichina (Lamiaceae)

Molecular Ecology, Volume 35, Issue 3, February 2026.
ABSTRACT Understanding gene flow between ploidy levels in polyploid complexes is essential for species delimitation and conservation. This study explores evolutionary dynamics in the polyploid complex Thymus sect. Mastichina (Lamiaceae), comprising three taxa: T. mastichina subsp. mastichina, T. mastichina subsp.
Francisco José García‐Cárdenas, María Ángeles Ortiz, José Carlos del Valle, David Doblas‐Pruvost, Manuel de la Estrella, Diego Nieto‐Lugilde, Lisa Pokorny, Regina Berjano   +7 more
wiley   +1 more source

Multi-dimensional regional inequality as an alternative allocation mechanism For EU Structural Funds remittances: The case of Spain and Hungary [PDF]

, 2005
R58, R15,
Wim Heijman, Heijman, W.J.M., Henk Folmer, Folmer, H.   +3 more
core   +1 more source

Pulmonary‐Targeted Nanoparticles Interrupt the Malignant Mechanical and Biochemical Signaling Crosstalk for Idiopathic Pulmonary Fibrosis Therapy

Advanced Science, Volume 13, Issue 5, 27 January 2026.
Idiopathic pulmonary fibrosis (IPF) progression is driven by TGF‐β induced biochemical signals and mechanical signals from increased ECM stiffness. Pulmonary‐targeted VB‐RT NPs not only eliminate excessive ROS and penetrate the dense ECM collagen barrier via NO release, but also simultaneously interrupt the persistent malignant between mechanical and ...
Xue‐Na Li, Ya‐Ping Lin, Xi‐Xi Ma, Yue‐Fei Fang, Hui Wang, Chun‐Hui Cui, Chen Zhang, Jin‐You Piao, Jee‐Heon Jeong, Xian Wu Cheng, Lei Xing, Hu‐Lin Jiang   +11 more
wiley   +1 more source

Unveiling Antimalarial Drug Resistance: The Role of CRISPR‐Cas Technologies in Malaria Research

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background Malaria, caused by Plasmodium parasites, remains a global health burden, with drug resistance threatening control efforts. CRISPR‐Cas technologies, particularly CRISPR‐Cas9, have transformed malaria research by enabling precise genetic manipulations to study antimalarial resistance mechanisms, develop novel therapeutics and enhance ...
Reuben Samson Dangana, Israel Ehizuelen Ebhohimen, Moses Okpeku, Jess Vergis   +3 more
wiley   +1 more source

“Absorption” or “Carrying Capacity” of Areas – Assessment Methods on the Example of Detached Housing Real Estate

Real Estate Management and Valuation, 2019
The concept of market absorption and carrying capacity in economic terms are adequate to the real estate market, even though the legislator uses only the concept of the absorptive capacity of the area in the planning process.
Foryś Iwona, Kazak Jan
doaj   +1 more source

A Cell‐Penetrating Scorpion Venom Peptide Disrupts the HSP90β‐PPARα Interaction to Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease

iMetaMed, Volume 1, Issue 2, December 2025.
In MASLD, increased HSP90β interacts with PPARα, thereby inhibiting PPARα activation via the inhibition of its nuclear translocation. BmK Tx‐2, a cell‐penetrating peptide from Buthus martensii Karsch scorpion venom, enters hepatocytes via macropinocytosis and escapes endosomes to bind HSP90β.
Erjin Xu, Wuguang Lu, Yonggen Chen, Ming Sang, Jiao Chen, Xueting Cai, Wenhao Xu, Yuxin Zhang, Zhiheng Wang, Feng Zhang, Peng Cao   +10 more
wiley   +1 more source