Results 111 to 120 of about 21,652,589 (289)
Factor structure of the Life Orientation Test-Revised (LOT-R)
Acta Colombiana de Psicología, 2017 Optimism and pessimism are conceptualized as generalized expectations about events happening in people's lives, and are regarded as stable dispositions. The construct of optimism can be understood as being one-dimensional and bipolar, in other words, it ...
Fernanda Ottati, Ana Paula Porto Noronha
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Environmental regulation, R&D subsidies, and industrial green total factor productivity
Sustainable FuturesIn the face of worsening global environmental degradation, significant attention has been devoted to the greening of industrial transformation and development, specifically by improving industrial green total factor productivity (GTFP).
Bu Wei, Li Chenxi, Liu Shanshan
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Modeling of the Rainfall and R-Factor for Tocantins State, Brazil
Revista Brasileira de Ciência do SoloThe state of Tocantins is inserted in the new Brazilian agricultural frontier and has shown enormous potential for expansion of the agricultural lands.
Junior Cesar Avanzi +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Evaluation of Seismic Performance Parameters of Steel Moment Frames Using Conventional and Advanced Pushover Methods with Considering Higher Mode and Near Field Pulse-Type Effects [PDF]
Journal of Structural and Construction Engineering, 2016 Ductility, over-strength, material properties and design methodology are the factors affect the reduction rate of the lateral strength of structure in nonlinear region.
Navid Siahpolo +2 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source