Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Individual differences in bottom-up and top-down emotion generation. [PDF]
Kako N, Rozenman M, Dumas D, McRae K.
europepmc +1 more source
S, Mitsuhashi +4 more
openaire +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Polyethylene glycol-conjugated recombinant human granulocyte colony-stimulating factor (PEG-rhG-CSF) primary prophylaxis significantly reduces the duration of neutropenia in non-Hodgkin's lymphoma patients treated with chemotherapy: a randomised trial (NCT05834751). [PDF]
Wang B +8 more
europepmc +1 more source
Protective effects of naringenin and naringin in organ ischemia/reperfusion injuries: a comprehensive narrative review. [PDF]
Hou M, Wei D, Wang Y, Zhang X, Yao Z.
europepmc +1 more source
Tissue factor detection in mouse tissues by western blotting using commercial antibodies. [PDF]
Perkins MV +3 more
europepmc +1 more source
Development and Validation of the Parental Media Motivations (MEMO) Scales for Child and Parent Media Use in the United States. [PDF]
Suh B +4 more
europepmc +1 more source
Objective tremor monitoring using tri-axis accelerometer in MRgFUS thalamotomy for essential tremor: a feasibility study. [PDF]
Liu KC +7 more
europepmc +1 more source
Translation and Validation of the Arabic Version of the Revised Restrictive Behaviours Scale Among Iraqi Children With Autism Spectrum Disorder: A Suggestion for Model Modification. [PDF]
Hussein Al-Sultan RR +6 more
europepmc +1 more source

