Results 101 to 110 of about 3,104,231 (310)

seedset_appendixS2_GambelHolway2023.R

open access: yes, 2023
R code for seed set analysis (Appendix S2)
Jess Gambel (15347551)
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

seedset_maindoc_GambelHolway2023.R

open access: yes, 2023
R code for seed set analysis (Main Document)
Jess Gambel (15347551)
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Summary of the First Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE1)

open access: yes, 2014
Challenges related to development, deployment, and maintenance of reusable software for science are becoming a growing concern. Many scientists’ research increasingly depends on the quality and availability of software upon which their works are built ...
Ketan Maheshwari   +35 more
core   +1 more source

fruitset_appendixS2_GambelHolway2023.R

open access: yes, 2023
R code for fruit set analysis (Appendix S2)
Jess Gambel (15347551)
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Preparation of RGO/NiO Anode for Lithium-ion Batteries

open access: yesInternational Journal of Electrochemical Science, 2019
As an efficient and stable energy storage device, lithium-ion batteries (LIBs) have become an important part of today’s society and are widely used in production and life.
Shiyi Tian   +4 more
doaj   +1 more source

Comprehensive health risk analysis of heavy metal pollution using water quality indices and Monte Carlo simulation in R software. [PDF]

open access: yesSci Rep, 2023
Badeenezhad A   +8 more
europepmc   +1 more source

microniches_18S_v1.R

open access: yes, 2022
eukaryotic community bargraph R ...
FRANCESCO RICCI (4362436)
core   +1 more source

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