Results 121 to 130 of about 3,104,231 (310)

A survey of software development practices in the New Zealand software industry

open access: yes, 2000
We report on the software development techniques used in the New Zealand software industry, paying particular attention to requirements gathering. We surveyed a selection of software companies with a general questionnaire and then conducted in-depth ...
Greg Reeve   +9 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Pengenalan Software R

open access: yes, 2019
Materi pengenalan software R yang dipaparkan pada Pelatihan Software R. Pelatihan ini diselenggarakan oleh PPI Austria 2019 di Vienna.
openaire   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Machine learning-aided first-principles calculations of redox potentials

open access: yesnpj Computational Materials
We present a method combining first-principles calculations and machine learning to predict the redox potentials of half-cell reactions on the absolute scale.
Ryosuke Jinnouchi   +2 more
doaj   +1 more source

Cost-Efficient and Quality of Experience-Aware Provisioning of Virtual Machines for Multiplayer Cloud Gaming in Geographically Distributed Data Centers

open access: yesIEEE Access, 2019
Prompted by the remarkable progress in both cloud computing and GPU virtualization, cloud gaming has become increasingly more popular in the gaming industry.
Yongqiang Gao, Lin Wang, Jiantao Zhou
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy