Results 131 to 140 of about 3,104,231 (310)
Evolutionary success of open source software: An investigation into exogenous drivers
, 2007 Copyright @ 2007 EASSTThe “success” of a Free/Libre/Open Source Software (FLOSS) project has often been evaluated through the number of commits made to its configuration management system, number of developers and number of users.
Rank, S +8 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
HOW TO PERFORM A META-ANALYSIS: A PRACTICAL STEP-BY-STEP GUIDE USING R SOFTWARE AND RSTUDIO. [PDF]
Acta Ortop Bras, 2022 Ariel de Lima D +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
PED-R. Pedigree Matrix with R for Windows. Version 1.1
, 2017 PED-R is a software to calculate easily the Pedigree matrix using R (statistical software). PED-R provides the Pedigree matrix in csv format and txt format which can be used by GAP software to show heatmaps.
Alvarado, Gregorio +5 more
core
Support for evolving software architectures in the ArchWare ADL
, 2011 Software that cannot evolve is condemned to atrophy: it cannot accommodate the constant revision and re-negotiation of its business goals nor intercept the potential of new technology.
Balasubramaniam, Dharini +17 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Fracture and Structural Integrity, 2018 The simulation of the fatigue damage of laminated composites under multi-axial and variable amplitude loadings has to deal with several new challenges and several methods of damage modelling.
Michael Hack +7 more
doaj
Cgmquantify: Python and R Software Packages for Comprehensive Analysis of Interstitial Glucose and Glycemic Variability from Continuous Glucose Monitor Data. [PDF]
IEEE Open J Eng Med Biol, 2021 Bent B, Henriquez M, Dunn J.
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source