Results 81 to 90 of about 8,158,678 (300)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Selection of Statistical Software for Solving Big Data Problems for Teaching [PDF]

, 2017
The need for analysts with expertise in big data software is becoming more apparent in 4 today’s society. Unfortunately, the demand for these analysts far exceeds the number 5 available. A potential way to combat this shortage is to identify the software
Dou, Min, Li, Yang, Ozgur, Ceyhun, Rogers, Grace   +3 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Using entropy measures for comparison of software traces

, 2012
The analysis of execution paths (also known as software traces) collected from a given software product can help in a number of areas including software testing, software maintenance and program comprehension.
Davison, M., Miranskyy, A. V., Murtaza, S. S., Reesor, M.   +3 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Design and Achievement of User Interface Automation Testing of Linux Based on Element Tree of DogTail

ITM Web of Conferences, 2017
As Linux gets more popular around the world, the advantage of the open source on software makes people do automated UI test by unified testing framework.
Yuan Wen-Chao, Zhu Hong-Mei, Sun Zi-Qian
doaj   +1 more source

Pengenalan Software R

, 2019
Materi pengenalan software R yang dipaparkan pada Pelatihan Software R. Pelatihan ini diselenggarakan oleh PPI Austria 2019 di Vienna.
openaire   +1 more source

Software management tools: Lessons learned from use [PDF]

, 1985
Experience in inserting software project planning tools into more than 100 projects producing mission critical software are discussed. The problems the software project manager faces are listed along with methods and tools available to handle them ...
Knight, J., Reifer, D. J., Valett, J., Wenneson, G.   +3 more
core   +1 more source

Self-esteem, general and sexual self-concepts in blind people [PDF]

, 2015
Background: People with visual disability have lower self-esteem and social skills than sighted people. This study was designed to describe self-esteem and general and sexual self-concepts in blind people.
Azarbayejani, A., Salehi, M., Shafiei, K., Shayegh, B., Ziaei, T.   +4 more
core   +3 more sources