Function and regulation of Rab GTPases in cancers [PDF]
Cell Biology and ToxicologyThe Rab small GTPases are characterized by the distinct intracellular localization and modulate various endocytic, transcytic and exocytic transport pathways.
Shouying Xu +7 more
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Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiation [PDF]
eLifeRab-dependent membrane trafficking is critical for changing the structure and function of dendritic spines during synaptic plasticity. Here, we developed highly sensitive sensors to monitor Rab protein activity in single dendritic spines undergoing ...
Jie Wang +10 more
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İlk Dönem Tefsirlerinde Rab Kelimesine Yüklenen Anlamlara Arap Şiirinden İstişhad Örnekleri
Yakın Doğu Üniversitesi İslam Tetkikleri Merkezi DergisiKur’an’ın nazil olmaya başladığı ilk dönem Arap toplumu, Allah’a inanıyor ve Allah’ın her şeyin sahibi ve yaratıcısı olduğunu kabul ediyordu. Günlük konuşmalarında hem Allah hem de Allah’tan başka varlıklar; mesela melekler, hükümdarlar, putlar ve bazı ...
Abdullah Sevgi
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The Regulation of Rab GTPases by Phosphorylation
Biomolecules, 2021 Rab proteins are small GTPases that act as molecular switches for intracellular vesicle trafficking. Although their function is mainly regulated by regulatory proteins such as GTPase-activating proteins and guanine nucleotide exchange factors, recent ...
Lejia Xu +4 more
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LET-502/ROCK Regulates Endocytic Recycling by Promoting Activation of RAB-5 in a Distinct Subpopulation of Sorting Endosomes [PDF]
Cell Reports, 2020 Summary: To explore the mechanism of Rab5/RAB-5 activation during endocytic recycling, we perform a genome-wide RNAi screen and identify a recycling regulator, LET-502/ROCK.
Wenjuan Zhang +14 more
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Phosphorylation of Rab
Traffic : the International Journal of Intracellular Transport, 2020 Rab GTPases are master regulators of membrane trafficking in eukaryotic cells. Phosphorylation of Rab GTPases was characterized in the 1990s and there have been intermittent reports of its relevance to Rab functions.
Dieter Waschbüsch, Amir R. Khan
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PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
eLife, 2019 Mutations that activate LRRK2 protein kinase cause Parkinson’s disease. LRRK2 phosphorylates a subset of Rab GTPases within their Switch-II motif controlling interaction with effectors.
Kerryn Berndsen +11 more
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Claudin and Rab proteins are key molecular components involved in coccidiosis resistance in Portuguese Merino sheep. [PDF]
Genet Sel EvolVarela-Martínez E +15 more
europepmc +2 more sources
Psychiatric treatment of mentally ill persons in custody – legal, medical and ethical issues
European Psychiatry, 2021 Introduction The most recent legal regulations in the Republic of Croatia govern the process of criminal procedure for persons in pre-trial detention who have a temporary mental disturbance for which psychiatric treatment is needed. The Prison Director
V. Sendula Jengic, A. Jengic Bujan
doaj +1 more source
Journal of Cell Biology, 2021 Borchers et al. review regulatory principles in the activation of endocytic Rab GTPases and how they apply to other Rab and Arf GTPases.
Ann-Christin Borchers +2 more
semanticscholar +1 more source