Results 11 to 20 of about 54,351 (195)

Structure of Rab Escort Protein-1 in Complex with Rab Geranylgeranyltransferase [PDF]

open access: yesMolecular Cell, 2003
Posttranslational geranylgeranylation of Rab GTPases is catalyzed by Rab geranylgeranyltransferase (RabGGTase), which consists of a catalytic alpha/beta heterodimer and an accessory Rab escort protein (REP). The crystal structure of isoprenoid-bound RabGGTase complexed to REP-1 has been solved to 2.7 A resolution.
Pylypenko, Olena   +11 more
openaire   +5 more sources

Technical Guidance for Making Budget Plans in Kedungrejo Village, Rembang Regency

open access: yesJurnal Pemberdayaan Masyarakat Madani, 2022
In building a village infrastructure, it is necessary to calculate the costs contained in the Budget Plan (RAB) according to the standards set by the government. The RAB provides an overview of the costs required to construct a structure or building.
Hendra Masvika, Hani Purwanti
doaj   +1 more source

Rab GTPases at a glance [PDF]

open access: yesJournal of Cell Science, 2007
It has been two decades since the yeast Ypt1 and Sec4 proteins and the mammalian Rab (Ras-related proteins in brain) GTPases were first identified as evolutionarily conserved, essential regulators of membrane trafficking ([Salminen and Novick, 1987][1]; [Schmitt et al., 1986][2]; [Touchot et al.,
Schwartz, Samantha   +4 more
openaire   +4 more sources

KRIZNA STANJA I PRIMJENA MJERA PRISILE U PSIHIJATRIJI

open access: yesZbornik Pravnog Fakulteta Sveučilišta u Rijeci, 2017
U radu se raspravlja o fenomenu agresivnosti i nasilja kod čovjeka, s posebnim osvrtom na duševno oboljele. Krizno stanje i nasilno ponašanje ne događa se samo u psihijatriji.
Vesna Šendula Jengić, Sanja Katalinić
doaj   +1 more source

A potent and selective small molecule inhibitor of myoferlin attenuates colorectal cancer progression

open access: yesClinical and Translational Medicine, 2021
As a pivotal vesicular trafficking protein, Myoferlin (MYOF) has become an attractive target for cancer therapy. However, the roles of MYOF in colorectal cancer invasion remain enigmatic, and MYOF‐targeted therapy in this malignancy has not been explored.
Yuan He   +12 more
doaj   +1 more source

Defects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function.

open access: yesFrontiers in Neuroscience, 2015
The Conserved Oligomeric Golgi (COG) complex is an evolutionarily conserved hetero-octameric protein complex that has been proposed to organize vesicle tethering at the Golgi apparatus.
Leslie K Climer   +2 more
doaj   +1 more source

MOLECULAR MACHINES DETERMINING THE FATE OF ENDOCYTOSED SYNAPTIC VESICLES IN NERVE TERMINALS

open access: yesFrontiers in Synaptic Neuroscience, 2016
The cycle of a synaptic vesicle (SV) within the nerve terminal is a step-by-step journey with the final goal of ensuring the proper synaptic strength under changing environmental conditions.The SV cycle is a precisely regulated membrane traffic event in ...
Anna eFassio   +4 more
doaj   +1 more source

Ay, There’s the Rab: Organelle Maturation by Rab Conversion [PDF]

open access: yesDevelopmental Cell, 2005
Is endocytosed cargo transported by vesicular intermediates between early and late endosomes, or does an endosome mature while its cargo remains in place? Current work suggests that the latter takes place within the endosomal system via a process termed Rab conversion.
openaire   +2 more sources

Nove spoznaje o korskim sjedalima u crkvi Uznesenja Blažene Djevice Marije u Rabu

open access: yesArs Adriatica, 2019
Istraživanja kasnogotičkih korskih sjedala koja je Hrvatski restauratorski zavod proveo 2018. godine u župnoj crkvi, negdašnjoj katedrali Uznesenja Blažene Djevice Marije u Rabu upućuju na postupan tijek gradnje klupa koji se odvijao u fazama, a dovršen ...
Ksenija Škarić, Vanesa Gjini
doaj   +1 more source

Deregulation of Rab and Rab Effector Genes in Bladder Cancer

open access: yesPLoS ONE, 2012
Growing evidence indicates that Rab GTPases, key regulators of intracellular transport in eukaryotic cells, play an important role in cancer. We analysed the deregulation at the transcriptional level of the genes encoding Rab proteins and Rab-interacting proteins in bladder cancer pathogenesis, distinguishing between the two main progression pathways ...
Ho, Joel   +9 more
openaire   +5 more sources

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