Results 191 to 200 of about 73,139 (321)

Severity bands for atopic dermatitis measures: Analysis from adult dupilumab randomized clinical trials

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This analysis used a large clinical trial data set (>30,000 patient visits across >2800 patients) and novel statistical methodologies (including frequency cross‐over analysis and means based on spline regression) to develop severity threshold bands for clinician‐ and patient‐reported outcome measures for adults with moderate‐to‐severe atopic dermatitis.
Andreas Wollenberg   +7 more
wiley   +1 more source

A proximity map of RAB GTPases delineates roles for RAB14 in EARP complex and UHRF1BP1 endosomal recruitments. [PDF]

open access: yesCommun Biol
Gaudreault V   +9 more
europepmc   +1 more source

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

open access: yesJournal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads   +8 more
wiley   +1 more source

SNX-3 confers lysosomal fusion-competence to sustain basal autophagy. [PDF]

open access: yesCell Mol Life Sci
Kang Q   +5 more
europepmc   +1 more source

Was the evolution of faster stomata driven by increased gas exchange rates rather than increasing water use efficiency?

open access: yesNew Phytologist, EarlyView.
Summary Following changes in light flux, photosynthesis (A) typically adjusts more quickly than stomatal conductance (gs), which is dependent on changes in stomatal aperture. Faster stomatal responses are proposed to reduce water loss and enhance growth in dynamic light environments. Stomatal opening and closing parameters were determined in a range of
Robert A. Brench   +4 more
wiley   +1 more source

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