Results 241 to 250 of about 73,139 (321)

Individual alpha frequency tACS modifies the detection of space-time optical illusion. [PDF]

Exp Brain Res
Neri F, Catrambone V, Cinti A, Scoccia A, Benelli A, Romanella S, Grabot L, Valenza G, Smeralda CL, Santarnecchi E, van Wassenhove V, Rossi S.   +11 more
europepmc   +1 more source

Allosteric regulation of the Golgi-localized PPM1H phosphatase by Rab GTPases modulates LRRK2 substrate dephosphorylation in Parkinson's disease. [PDF]

J Biol Chem
Adhikari A, Tripathi A, Chiang CY, Sherpa P, Pfeffer SR.   +4 more
europepmc   +1 more source

Synaptic Vesicle Glycoprotein 2A Suppresses Amyloidogenesis Beyond Its Synaptic Role: A Novel Mechanism Disrupting BACE1 Binding and Altering APP Localization

Aging Cell, Volume 25, Issue 2, February 2026.
Synaptic vesicle glycoprotein 2A, the newly identified APP‐binding protein, reduces amyloid‐β plaque deposition in Alzheimer's disease by suppressing the amyloidogenic pathway through inhibition of BACE1‐APP interaction and alteration of APP endosomal‐lysosomal localization.
Xiaoling Wang, Qian Zhang, Xiaomin Zhang, Jing Liu, Jingjing Zhang, Congcong Liu, Yuting Cui, Qiao Song, Yuli Hou, Yaqi Wang, Min Cao, Peichang Wang   +11 more
wiley   +1 more source

GPNMB, LRRK2, and lysosome exocytosis in Parkinson's. [PDF]

Sci Adv
Pfeffer SR.
europepmc   +1 more source

Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Mouse models revealed age‐associated increased circumferential stiffness of the proximal pulmonary artery that was associated with reorientation of collagen and decreased function of the lung and right ventricle. Age‐related transcriptional changes were indicative of senescence, ECM turnover, TGFβ signaling, and altered intercellular signaling among ...
Ruben De Man, Zhongyu Cai, Pramath Doddaballapur, Nicole Guerrera, Alexandria Regan, Liqin Lin, Erica Schwarz, Aurelien Justet, Nebal S. Abu Hussein, Jack Di Palo, Cristina Cavinato, Micha Sam B. Raredon, Paul M. Heerdt, Inderjit Singh, Xiting Yan, Min‐Jong Kang, Danielle R. Bruns, Patty J. Lee, George Tellides, Jay D. Humphrey, Naftali Kaminski, Abhay B. Ramachandra, Edward P. Manning   +22 more
wiley   +1 more source

Correction to: Diagnosis and treatment of iron deficiency in chronic heart failure. [PDF]

Wien Klin Wochenschr
Messner M, Pölzl G, Adlbrecht C, Altenberger J, Auer J, Berent R, Dörler J, Zaruba MM, Ebner C, Fruhwald F, Hülsmann M, Mörtl D, Rainer PP, Rab A, Weber T, Berger R, Heart Failure Working Group of The Austrian Society for Cardiology.   +16 more
europepmc   +1 more source

Research Progress of Exosome‐Derived microRNA in Alcohol Use Disorders: A Critical Review

Addiction Biology, Volume 31, Issue 2, February 2026.
Exosome‐derived microRNAs represent stable and mechanistically active mediators of alcohol‐induced multi‐organ injury. This review summarizes how chronic alcohol exposure reshapes exosomal miRNA cargo across the liver, immune system, and brain, highlighting key miRNAs with diagnostic value and therapeutic potential.
Bo Zhang, Ting ting Xie, Qiang Ma, Ya ping Jiang, Yu mei Wang   +4 more
wiley   +1 more source

Exploring the Anticancer Potential of Proton Pump Inhibitors by Targeting GRP78 and V-ATPase: Molecular Docking, Molecular Dynamics, PCA, and MM-GBSA Calculations. [PDF]

Int J Mol Sci
Elfiky AA, Mansour KR, Mohamed Y, Abdelaziz YK, Nicholls IA.   +4 more
europepmc   +1 more source

Proteomic profiling of porcine seminal extracellular vesicles reveals potential in vivo fertility biomarkers

Andrology, Volume 14, Issue 2, Page 555-570, February 2026.
Abstract Background Predicting male fertility in farm animals remains a challenge. Seminal plasma (SP) contains a high amount of heterogeneous seminal extracellular vesicles (sEVs), believed involved in reproductive processes and maybe key to understanding male fertility.
Isabel Barranco, Pablo Martínez‐Díaz, Ana Parra, María José Martínez‐Alborcia, Xiomara Lucas, Heriberto Rodríguez‐Martínez, Jordi Roca   +6 more
wiley   +1 more source

Heat shock proteins at the crossroads of endosomal trafficking pathways. [PDF]

Cell Biol Toxicol
Zuppini F, Renzullo L, Tornatore F, Poggio P, Brancaccio M.   +4 more
europepmc   +1 more source