Results 21 to 30 of about 244,605 (365)
Golgi-associated Rab GTPases implicated in autophagy
Cell & Bioscience, 2021 Autophagy is a conserved cellular degradation process in eukaryotes that facilitates the recycling and reutilization of damaged organelles and compartments.
Q. Lu, Po-shun Wang, Ling Yang
semanticscholar +1 more source
Warburg Micro syndrome is caused by RAB18 deficiency or dysregulation [PDF]
Open Biology, 2015 RAB18, RAB3GAP1, RAB3GAP2 and TBC1D20 are each mutated in Warburg Micro syndrome, a rare autosomal recessive multisystem disorder. RAB3GAP1 and RAB3GAP2 form a binary ‘RAB3GAP’ complex that functions as a guanine-nucleotide exchange factor (GEF) for ...
Mark T. Handley +6 more
doaj +1 more source
Structure of Rab Escort Protein-1 in Complex with Rab Geranylgeranyltransferase [PDF]
Molecular Cell, 2003 Posttranslational geranylgeranylation of Rab GTPases is catalyzed by Rab geranylgeranyltransferase (RabGGTase), which consists of a catalytic alpha/beta heterodimer and an accessory Rab escort protein (REP). The crystal structure of isoprenoid-bound RabGGTase complexed to REP-1 has been solved to 2.7 A resolution.
Pylypenko, Olena +11 more
openaire +7 more sources
Bayesian Self‐Optimization for Telescoped Continuous Flow Synthesis
Angewandte Chemie International Edition, Volume 62, Issue 3, January 16, 2023., 2023 An autonomous continuous flow platform for the rapid development of multistep synthetic pathways is reported. New multipoint sampling and Bayesian optimization techniques were combined, enabling simultaneous identification of optimum reaction conditions within a pharmaceutical process. The short optimization times achieved are promising for development
Adam D. Clayton +9 more
wiley +1 more source
eLife, 2021 Rab GTPases are molecular switches that regulate membrane trafficking in all cells. Neurons have particular demands on membrane trafficking and express numerous Rab GTPases of unknown function.
F. E. Kohrs +12 more
semanticscholar +1 more source
Koja je formula kvalitetnoga odgoja?
Diacovensia, 2022 Što je dobar odgoj s obzirom na kvalitete koje iz njega trebaju proizići? Kako znamo da smo dobro odgojili dijete? I koje mu kvalitete trebamo usaditi?
Petra Domaćinović +1 more
doaj +1 more source
PELATIHAN PENYUSUNAN RAB (RENCANA ANGGARAN BIAYA) BAGI APARAT KAMPUNG SEKBAN DISTRIK PARIWARI KABUPATEN FAKFAK PROVINSI PAPUA BARAT [PDF]
, 2023 bstrak: Saat ini pembangunan infrastruktur sangat masif dilakukan tidak terkecuali di daerah-daerah pelosok. Hal ini tidak terlepas dengan adanya kebijakan pembangunan infrastruktur yang dapat menggunakan Dana Kampung.
Lomo, Supriyani +4 more
core +1 more source
Exosomes and their roles in the chemoresistance of pancreatic cancer
Cancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022 Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan +4 more
wiley +1 more source
Jurnal Surya Masyarakat, 2021 The main factor for the success of the implementation of education in schools is the infrastructure in the form of completeness of facilities that become the benchmark in all learning activities.
Emil Adly +4 more
doaj +1 more source
Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways [PDF]
, 2007 Rab family guanosine triphosphatases (GTPases) together with their regulators define specific pathways of membrane traffic within eukaryotic cells. In this study, we have investigated which Rab GTPase-activating proteins (GAPs) can interfere with the ...
Barr, Francis A. +5 more
core +2 more sources