Pyruvate Kinase Function Correlates With Red Blood Cell Properties and Clinical Manifestations in Sickle Cell Disease. [PDF]
ABSTRACT Pyruvate kinase (PK) is a key enzyme involved in the final step of glycolysis, essential to produce adenosine triphosphate (ATP). Relatively decreased red blood cell (RBC) PK activity (reflected by a lower PK/hexokinase [HK] ratio) and PK thermostability (PK activity after exposure to heat) were recently identified as pathophysiological ...
Traets MJM+17 more
europepmc +2 more sources
Custom in context : Medieval and Early Modern Scotland and England [PDF]
Studying custom and its context gives unique insights into relations of property, production and law in a society. The first part of the article discusses meaning in Scotland, focusing on ‘custom as normative practice, custom as unwritten law, and custom
Houston, Robert (Rab)
core +1 more source
Multisubunit members of the CATCHR family: COG and NRZ complexes, mediate intra-Golgi and Golgi to ER vesicle tethering, respectively. We systematically addressed the genetic and functional interrelationships between Rabs, Kifs, and the retrograde CATCHR
Shijie Liu+8 more
doaj +1 more source
What did the Royal Almoner do in Britain and Ireland, c.1450-1700? [PDF]
The late medieval and early modern royal almoner for England and Wales was an important figure, a senior cleric best documented as a court preacher who was the crown’s religious and moral face; prominent holders included Wolsey and Lancelot Andrewes. The
Houston, Robert (Rab)
core +1 more source
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases
Mutations in Park8, encoding for the multidomain Leucine-rich repeat kinase 2 (LRRK2) protein, comprise the predominant genetic cause of Parkinson's disease (PD).
Martin Steger+16 more
semanticscholar +1 more source
Construction of a Plasmodium falciparum Rab-interactome identifies CK1 and PKA as Rab-effector kinases in malaria parasites [PDF]
Background information The pathology causing stages of the human malaria parasite Plasmodium falciparum reside within red blood cells that are devoid of any regulated transport system.
Bourdoncle, P.+9 more
core +1 more source
Deregulation of Rab and Rab Effector Genes in Bladder Cancer
Growing evidence indicates that Rab GTPases, key regulators of intracellular transport in eukaryotic cells, play an important role in cancer. We analysed the deregulation at the transcriptional level of the genes encoding Rab proteins and Rab-interacting proteins in bladder cancer pathogenesis, distinguishing between the two main progression pathways ...
Bruno Goud+16 more
openaire +8 more sources
Robust Adaptive Beamforming for General-Rank Signal Model with Positive Semi-Definite Constraint via POTDC [PDF]
The robust adaptive beamforming (RAB) problem for general-rank signal model with an additional positive semi-definite constraint is considered. Using the principle of the worst-case performance optimization, such RAB problem leads to a difference-of ...
Khabbazibasmenj, Arash+1 more
core +1 more source
Ay, There’s the Rab: Organelle Maturation by Rab Conversion [PDF]
Is endocytosed cargo transported by vesicular intermediates between early and late endosomes, or does an endosome mature while its cargo remains in place? Current work suggests that the latter takes place within the endosomal system via a process termed Rab conversion.
openaire +3 more sources
KRIZNA STANJA I PRIMJENA MJERA PRISILE U PSIHIJATRIJI
U radu se raspravlja o fenomenu agresivnosti i nasilja kod čovjeka, s posebnim osvrtom na duševno oboljele. Krizno stanje i nasilno ponašanje ne događa se samo u psihijatriji.
Vesna Šendula Jengić, Sanja Katalinić
doaj +1 more source