The Emerging Functions of LRRK2 and Rab GTPases in the Endolysosomal System
Frontiers in Neuroscience, 2020 The leucine-rich repeat kinase 2 (LRRK2), the most common causative gene for autosomal-dominant familial Parkinson’s disease, encodes a large protein kinase harboring multiple characteristic domains.
Tomoki Kuwahara, T. Iwatsubo
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Effect of vine and fruit pruning on yield attributes of two watermelon (Citrullus lanatus) cultivars
Advances in Horticultural Science, 2021 This study was carried out to determine the effect of vine and fruit pruning on watermelon (Citrullus lanatus) yield. Five pruning methods: P1=no pruning at all, P2=pruning to four vines with two fruits per vine, P3=pruning to four vines with one fruit ...
Assinapol Ndereyimana +5 more
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Rab GTPases: Key players in melanosome biogenesis, transport, and transfer
Pigment Cell & Melanoma Research, 2020 Melanosomes are specialized intracellular organelles that produce and store melanin pigments in melanocytes, which are present in several mammalian tissues and organs, including the skin, hair, and eyes. Melanosomes form and mature stepwise (stages I–IV)
M. Fukuda
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α1B-adrenergic receptors differentially associate with Rab proteins during homologous and heterologous desensitization. [PDF]
PLoS ONE, 2015 Internalization of G protein-coupled receptors can be triggered by agonists or by other stimuli. The process begins within seconds of cell activation and contributes to receptor desensitization.
Jean A Castillo-Badillo +5 more
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Phosphorylation of small GTPase Rab proteins from Bombyx mori (Lepidoptera: Bombycidae)
European Journal of Entomology, 2009 Small GTPases of the Rab family act as essential regulators of vesicle transport pathways. Five Rab cDNA clones (BRab1, 7, 8, 11 and 14) from Bombyx mori were expressed in Escherichia coli as a thioredxin or glutathione sulfotransferase fusion protein ...
Tomohide UNO +10 more
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Roles of membrane trafficking in plant cell wall dynamics
Frontiers in Plant Science, 2015 The cell wall is one of the characteristic components of plant cells. The cell wall composition differs among cell types and is modified in response to various environmental conditions.
Kazuo eEbine +2 more
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RAB-6.1 and RAB-6.2 Promote Retrograde Transport in C. elegans. [PDF]
PLoS ONE, 2016 Retrograde transport is a critical mechanism for recycling certain membrane cargo. Following endocytosis from the plasma membrane, retrograde cargo is moved from early endosomes to Golgi followed by transport (recycling) back to the plasma membrane.
Donglei Zhang +3 more
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The puzzle of chloroplast vesicle transport – involvement of GTPases
Frontiers in Plant Science, 2014 In the cytosol of plant cells vesicle transport occurs via secretory pathways among the endoplasmic reticulum (ER) network, Golgi bodies, secretory granules, endosome and plasma membrane.
Sazzad eKarim, Henrik eAronsson
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New insights into the function of Rab GTPases in the context of exosomal secretion
Small GTPases, 2017 In the last two decades, extracellular vesicle-mediated communication between cells has become a major field in cell biology. However, the function of extracellular vesicles is far from clear, especially due to the disparity of released vesicles by cells.
L. Blanc, M. Vidal
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C9orf72’s interaction with Rab GTPases - modulation of membrane traffic and autophagy
Frontiers in Cellular Neuroscience, 2016 Hexanucleotide repeat expansion in an intron of Chromosome 9 open reading frame 72 (C9orf72) is the most common genetic cause of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD).
Bor Luen Tang
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