Results 41 to 50 of about 244,605 (365)
Neural Regeneration Research, 2019 Membrane trafficking processes are presumably vital for axonal regeneration after injury, but mechanistic understanding in this regard has been sparse. A recent loss-of-function screen had been carried out for factors important for axonal regeneration by cultured cortical neurons and the results suggested that the activity of a number of Rab GTPases ...
Cheryl Qian Ying Yong, Bor Luen Tang
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Nove spoznaje o korskim sjedalima u crkvi Uznesenja Blažene Djevice Marije u Rabu
Ars Adriatica, 2019 Istraživanja kasnogotičkih korskih sjedala koja je Hrvatski restauratorski zavod proveo 2018. godine u župnoj crkvi, negdašnjoj katedrali Uznesenja Blažene Djevice Marije u Rabu upućuju na postupan tijek gradnje klupa koji se odvijao u fazama, a dovršen ...
Ksenija Škarić, Vanesa Gjini
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Current Protocols in Cell Biology, 2012 AbstractThis unit describes methods to identify proteins interacting with, and regulating, Rab GTPases. Rabs form the largest subgroup of Ras superfamily GTPases, and act as molecular switches controlling the specificity of membrane trafficking. The regulation and the signal readout of Rabs are mediated by four groups of proteins, the GDP‐GTP exchange ...
Langemeyer, L, Barr, F
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Journal of Computational Chemistry, Volume 44, Issue 3, Page 179-189, January 30, 2023., 2023 The bonding of the organometallic intermediate in Ullmann coupling reactions for on‐surface synthesis is revealed by quantitative analysis of surface bonding with benchmarking of all relevant computational parameters. Abstract On‐surface synthesis has become a thriving topic in surface science.
Jan‐Niclas Luy +5 more
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Defects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function.
Frontiers in Neuroscience, 2015 The Conserved Oligomeric Golgi (COG) complex is an evolutionarily conserved hetero-octameric protein complex that has been proposed to organize vesicle tethering at the Golgi apparatus.
Leslie K Climer +2 more
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Clinical and Translational Medicine, 2021 As a pivotal vesicular trafficking protein, Myoferlin (MYOF) has become an attractive target for cancer therapy. However, the roles of MYOF in colorectal cancer invasion remain enigmatic, and MYOF‐targeted therapy in this malignancy has not been explored.
Yuan He +12 more
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Are There Rab GTPases in Archaea? [PDF]
Molecular Biology and Evolution, 2016 A complex endomembrane system is one of the hallmarks of Eukaryotes. Vesicle trafficking between compartments is controlled by a diverse protein repertoire, including Rab GTPases. These small GTP-binding proteins contribute identity and specificity to the system, and by working as molecular switches, trigger multiple events in vesicle budding ...
Jaroslaw Surkont, José B. Pereira-Leal
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MOLECULAR MACHINES DETERMINING THE FATE OF ENDOCYTOSED SYNAPTIC VESICLES IN NERVE TERMINALS
Frontiers in Synaptic Neuroscience, 2016 The cycle of a synaptic vesicle (SV) within the nerve terminal is a step-by-step journey with the final goal of ensuring the proper synaptic strength under changing environmental conditions.The SV cycle is a precisely regulated membrane traffic event in ...
Anna eFassio +4 more
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Structures and functions of cilia during vertebrate embryo development
Molecular Reproduction and Development, Volume 89, Issue 12, Page 579-596, December 2022., 2022 Abstract Cilia are hair‐like structures that project from the surface of cells. In vertebrates, most cells have an immotile primary cilium that mediates cell signaling, and some specialized cells assemble one or multiple cilia that are motile and beat synchronously to move fluids in one direction.
Jeffrey D. Amack
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Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance LRRK2, a protein kinase related to Parkinson’s disease, is implicated in the maintenance of lysosomes, and a subset of Rab GTPases has been identified as bona fide substrates of LRRK2. Here, we reveal a key stress-responsive pathway composed
T. Eguchi +10 more
semanticscholar +1 more source