Results 61 to 70 of about 244,605 (365)

Roles of membrane trafficking in plant cell wall dynamics

open access: yesFrontiers in Plant Science, 2015
The cell wall is one of the characteristic components of plant cells. The cell wall composition differs among cell types and is modified in response to various environmental conditions.
Kazuo eEbine   +2 more
doaj   +1 more source

C9orf72’s interaction with Rab GTPases - modulation of membrane traffic and autophagy

open access: yesFrontiers in Cellular Neuroscience, 2016
Hexanucleotide repeat expansion in an intron of Chromosome 9 open reading frame 72 (C9orf72) is the most common genetic cause of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD).
Bor Luen Tang
doaj   +1 more source

Rab 25: Oncogenes and Tumor Suppressive of Cancer [PDF]

open access: yesE3S Web of Conferences, 2021
Rab 25 is a small GTPase belonging to the RAS (rat sarcoma) superfamily. It is expressed in epithelial cells only and serves as a regulator of various intracellular signaling pathways.
Chen Flora
doaj   +1 more source

The Emerging Functions of LRRK2 and Rab GTPases in the Endolysosomal System

open access: yesFrontiers in Neuroscience, 2020
The leucine-rich repeat kinase 2 (LRRK2), the most common causative gene for autosomal-dominant familial Parkinson’s disease, encodes a large protein kinase harboring multiple characteristic domains.
Tomoki Kuwahara, T. Iwatsubo
semanticscholar   +1 more source

Phosphorylation of small GTPase Rab proteins from Bombyx mori (Lepidoptera: Bombycidae)

open access: yesEuropean Journal of Entomology, 2009
Small GTPases of the Rab family act as essential regulators of vesicle transport pathways. Five Rab cDNA clones (BRab1, 7, 8, 11 and 14) from Bombyx mori were expressed in Escherichia coli as a thioredxin or glutathione sulfotransferase fusion protein ...
Tomohide UNO   +10 more
doaj   +1 more source

Rab GTPases: Key players in melanosome biogenesis, transport, and transfer

open access: yesPigment Cell & Melanoma Research, 2020
Melanosomes are specialized intracellular organelles that produce and store melanin pigments in melanocytes, which are present in several mammalian tissues and organs, including the skin, hair, and eyes. Melanosomes form and mature stepwise (stages I–IV)
M. Fukuda
semanticscholar   +1 more source

The puzzle of chloroplast vesicle transport – involvement of GTPases

open access: yesFrontiers in Plant Science, 2014
In the cytosol of plant cells vesicle transport occurs via secretory pathways among the endoplasmic reticulum (ER) network, Golgi bodies, secretory granules, endosome and plasma membrane.
Sazzad eKarim, Henrik eAronsson
doaj   +1 more source

Rab GTPases: master regulators that establish the secretory and endocytic pathways

open access: yesMolecular Biology of the Cell, 2017
Several of the most important discoveries in the field of membrane traffic have come from studies of Rab GTPases by Marino Zerial and Peter Novick and their colleagues.
S. Pfeffer
semanticscholar   +1 more source

TRAPP Complexes in Secretion and Autophagy

open access: yesFrontiers in Cell and Developmental Biology, 2016
TRAPP is a highly conserved modular multi-subunit protein complex. Originally identified as a transport protein particle with a role in endoplasmic reticulum-to-Golgi transport, its multiple subunits and their conservation from yeast to humans were ...
Jane J Kim   +2 more
doaj   +1 more source

Rabs in Signaling and Embryonic Development [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Rab GTPases play key roles in various cellular processes. They are essential, among other roles, to membrane trafficking and intracellular signaling events. Both trafficking and signaling events are crucial for proper embryonic development. Indeed, embryogenesis is a complex process in which cells respond to various signals and undergo dramatic changes
Sonya Nassari   +2 more
openaire   +3 more sources

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