Results 81 to 90 of about 244,605 (365)

Yeast Irc6p is a novel type of conserved clathrin coat accessory factor related to small G proteins. [PDF]

, 2012
Clathrin coat accessory proteins play key roles in transport mediated by clathrin-coated vesicles. Yeast Irc6p and the related mammalian p34 are putative clathrin accessory proteins that interact with clathrin adaptor complexes.
Cascio, Duilio, Costaguta, Giancarlo, Daboussi, Lydia, Gorynia, Sabine, Lorenz, Todd C, Payne, Gregory S   +5 more
core   +1 more source

Antibody Characterization Report for Rab-1A and Rab-1B

, 2023
Head-to-head comparison of available commercial antibodies against Rab1 proteins Rab-1A and Rab-1B by immunoblot (Western blot), immunoprecipitation and immunofluorescence.
Moleón, Vera Ruíz, Fotouhi, Maryam, Ryan, Joel, Ayoubi, Riham, González Bolívar, Sara, Reintsch, Wolfgang, Durcan, Thomas M., Brown, Claire M., McPherson, Peter S., Laflamme, Carl   +9 more
openaire   +2 more sources

Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Several genetic loci known to confer risk for Parkinson's disease (PD) function in lysosomal pathways. We systematically screened common variants linked to PD risk by genome‐wide association studies (GWAS) for impact on cerebrospinal fluid (CSF) proteins reflecting lysosomal function.
Hanwen Zhang, Daniel Kargilis, Thomas Tropea, John Robinson, Junchao Shen, Eliza M. Brody, Ann Brinkmalm, Simon Sjödin, Adama J. Berndt, Marc Carceles‐Cordon, EunRan Suh, Vivianna M. Van Deerlin, Kaj Blennow, Daniel Weintraub, Edward B. Lee, Henrik Zetterberg, Alice S. Chen‐Plotkin   +16 more
wiley   +1 more source

New insights into the function of Rab GTPases in the context of exosomal secretion

Small GTPases, 2017
In the last two decades, extracellular vesicle-mediated communication between cells has become a major field in cell biology. However, the function of extracellular vesicles is far from clear, especially due to the disparity of released vesicles by cells.
L. Blanc, M. Vidal
semanticscholar   +1 more source

The pathogen-occupied vacuoles of Anaplasma phagocytophilum and Anaplasma marginale interact with the endoplasmic reticulum

Frontiers in Cellular and Infection Microbiology, 2016
The genus Anaplasma consists of tick-transmitted obligate intracellular bacteria that invade white or red blood cells to cause debilitating and potentially fatal infections. A.
Hilary Kay Truchan, Chelsea Leigh Cockburn, Kathryn Shirley Hebert, Forgivemore eMagunda, Susan Marite Noh, Jason A Carlyon   +5 more
doaj   +1 more source

A 14‐Year Study of Serum Glial Fibrillary Acidic Protein and Total Tau in Premanifest Huntington's

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT There is a pressing need for blood biomarkers that can identify Huntington's disease (HD) gene carriers' proximity to manifest disease. We previously examined serial serum neurofilament light (NfL) concentrations in 21 premanifest HD gene carriers and 14 controls over 14 years, finding that NfL demonstrates high prognostic value and distinct ...
Natalia E. Owen, Zanna J. Voysey, Jonathan A. Holbrook, Maura Malpetti, Clara Le Draoulec, Lennart R. B. Spindler, Anna O. G. Goodman, Alpar S. Lazar, Roger A. Barker   +8 more
wiley   +1 more source

RAB-10 is Required for Endocytic Recycling in the Caenorhabditis elegans Intestine [PDF]

, 2006
The endocytic pathway of eukaryotes is essential for the internalization and trafficking of macromolecules, fluid, membranes, and membrane proteins. One of the most enigmatic aspects of this process is endocytic recycling, the return of macromolecules ...
Chen, Carlos Chih-Hsiung, Grant, Barth D, Lambie, Eric J, Mareiniss, Darren P, Schweinsberg, Peter J, Vashist, Shilpa   +5 more
core   +3 more sources

Direct Ink Writing of Conductive Hydrogels

Advanced Functional Materials, EarlyView.
This review examines the use of direct ink writing (DIW) for fabricating conductive hydrogels with customizable 3D structures. It outlines the rheological requirements for successful DIW, followed by an exploration of the materials and ink formulations used to impart electronic and/or ionic conductivity to hydrogels while maintaining printability ...
Monica Ho, Aline Braz Ramirez, Negar Akbarnia, Eric Croiset, Elisabeth Prince, Gerald G. Fuller, Milad Kamkar   +6 more
wiley   +1 more source

Fast‐tracking bespoke DNA reference database generation from museum collections for biomonitoring and conservation

Molecular Ecology Resources, EarlyView., 2022
Abstract Despite recent advances in high‐throughput DNA sequencing technologies, a lack of locally relevant DNA reference databases limits the potential for DNA‐based monitoring of biodiversity for conservation and biosecurity applications. Museums and national collections represent a compelling source of authoritatively identified genetic material for
Andrew Dopheide, Talia Brav‐Cubitt, Anastasija Podolyan, Richard A. B. Leschen, Darren Ward, Thomas R. Buckley, Manpreet K. Dhami   +6 more
wiley   +1 more source

Nucleotide Dependence of Rab Geranylgeranylation [PDF]

Journal of Biological Chemistry, 1996
Geranylgeranylation of Rab GTPases is an essential post-translational modification that enables Rabs to associate with intracellular membranes where they regulate exocytic and endocytic pathways. Geranylgeranylation is initiated by formation of a stable complex between newly synthesized Rab proteins and Rab escort protein (REP).
openaire   +2 more sources