, 2022 The incidence of ALS is rising, and with onset of the disease usually occurring around 50-60 years of age, an effective treatment is urgent. Many of the proposed ALS pathogenic mechanisms, including neuroinflammation and oxidative stress, are currently ...
Leonard, Claudia
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Identification of host factors involved in human cytomegalovirus replication, assembly and egress using a two-step siRNA screen [PDF]
, 2018 As obligate intracellular parasites, viruses are completely dependent on host factors for replication. Assembly and egress of complex virus particles, such as human cytomegalovirus (HCMV), are likely to require many host factors. Despite this, relatively
Lin, Yao-Tang +5 more
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Screening of Rabs that mediate the regulation of PPARγ2.
, 2022 (A–K) Rabs, such as Rab1B (A), Rab5A (B), Rab9A (C), Rab9B (D), Rab11B (E), Rab22B (F), Rab32 (G), Rab4B (H), Rab39A (I), Rab13 (J), and Rab23 (K), mediate the protein stability of exogenous PPARγ2 after gradient overexpression of different plasmids ...
Hong Yu Wang (10756167) +12 more
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Endosomal recycling Rabs increase in the early phase of DC maturation.
, 2013 Quantitative RT-PCR shows expression levels of the targeted Rab GTPases in moDCs, after LPS stimulation for the indicated time periods. All data are normalized to initial iDC expression levels. Rab4b (A) and Rab11a (B) are involved in short and long loop
Axel Berg-Larsen (454431) +4 more
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Understanding the Genetic Susceptibility and Epidemiologic Risk Factors of Intracranial Aneurysms
, 2015 Background and Objectives Intracranial aneurysms affect up to 3% of the population and carry a high mortality and morbidity prognosis when presented with aneurysm rupture and spontaneous subarachnoid hemorrhage (SAH).
Lai, Pui Man Rosalind
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Identification of novel candidate genes in East Asian COPD patients by the functional summary-based imputation and the unified test for molecular signatures: a transcriptome-wide association study. [PDF]
Chin Med J (Engl), 2023 Tian Y +8 more
europepmc +1 more source
Hesperetin Ameliorates Inhibition of Neuronal and Oligodendroglial Cell Differentiation Phenotypes Induced by Knockdown of Rab2b, an Autism Spectrum Disorder-Associated Gene Product. [PDF]
Neurol Int, 2023 Kato Y +9 more
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Co-Expression Analysis of Airway Epithelial Transcriptome in Asthma Patients with Eosinophilic vs. Non-Eosinophilic Airway Infiltration. [PDF]
Int J Mol Sci, 2023 Kozlik-Siwiec P +14 more
europepmc +1 more source
Rab GTPases: The principal players in crafting the regulatory landscape of endosomal trafficking. [PDF]
Comput Struct Biotechnol J, 2022 Zhang J, Jiang Z, Shi A.
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