Results 101 to 110 of about 2,160,348 (358)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

ENVIRONMENTAL CONDITIONS AS A PROVOCATIVE BACKGROUND FOR REPRODUCTION INDICES IN SABLES (MARTES ZIBELLINA) DIFFERING IN COAT PIGMENTATION HEAVINESS

Вавиловский журнал генетики и селекции, 2014
This work concerns sable domestication at Russian fur farms. There are two ecotypes of sables: (1) dark with small body size and poorly fertile and (2) diluted with large body size and more fertile. The former lives in Siberian pine forests with a stable
S. V. Beketov, T. I. Kazakova, I. E. Chernova   +2 more
doaj  

Cecal coccidiosis in Japanese quails (Coturnix Japonica): Eimeria tsunodai identification and comparative prophylactic phytochemotherapy with immune stimulant impact

Open Veterinary Journal
Background: Among the serious quail diseases is coccidiosis, caused by several Eimeria species, particularly cecal coccidiosis, with considerable economic losses. Aim: First, 11 quail flocks showing brownish diarrhea tinged with blood and bloody cecal
Reham M. ElBakrey, Amal A.M. Eid, Ahmed A. ElKholy, Mohamed R. Mousa, Mohamed A. El-Morsy, Walaa S. Abdelaziz   +5 more
doaj   +1 more source

Rabbit Syphilis Diagnosed Clinically in Household Rabbits

Journal of Veterinary Medical Science, 2003
This paper deals with 16 cases presented from April to December 2001 and diagnosed clinically as rabbit syphilis, because they showed distinct lesions around the nose and/or mouth, responded to chemotherapy, and the "Rapid Plasma Reagin" test was positive. Twelve cases exhibited initial symptoms and four were relapses.
Kumiko, Saito, Masayo, Tagawa, Atsuhiko, Hasegawa   +2 more
openaire   +3 more sources

HARMONIZATION OF CRITERIA AND TERMINOLOGY IN RABBIT MEAT RESEARCH

, 2010
The harmonization of rabbit carcass criteria is a result of an international work. lts task was to specify the main traits to be considerad from the birth of the animal to carcass analysis, to define these traits with enough accuracy and to propose a ...
A. Blasco, J. Ouhayoun, G. Masoero
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Abstracts of the 24th Hungary conference on rabbit production

World Rabbit Science, 2014
Some 100 guests took part in the 24th Hungarian Conference on Rabbit Production in Kaposvár, organised by the University of Kaposvár, the Hungarian Branch of the WRSA and the Rabbit Production Board.
24TH Conference on rabbit production Kaposvár, Hungary. 30th May, 2012
doaj   +1 more source

Local variation in absolute water content of human and rabbit eye lenses measured by Raman microspectroscopy [PDF]

, 1989
Raman spectra were obtained from fresh, fixed and sliced rabbit lenses and from human lens slices. For all lenses and lens slices the ratio R, defined as the Raman intensity at 3390 cm−1 divided by the Raman intensity at 2935 cm−1, was measured at ...
Bot, Annet C.C., Greve, Jan, Huizinga, Alex, Mul, Frits F.M. de, Vrensen, Gijs F.J.M.   +4 more
core   +4 more sources

LEUKOCYTE-DEPENDENT HISTAMINE RELEASE FROM RABBIT PLATELETS

Journal of Experimental Medicine, 1972
We have studied the leukocyte-dependent mechanism of histamine release (LDHR) from rabbit platelets, a complement-independent mechanism which has been implicated in the deposition of immune complexes in acute serum sickness of rabbits.
J. Benveniste, P. Henson, C. Cochrane
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source