Results 41 to 50 of about 2,160,348 (358)

Structure of rabbit liver fructose 1,6-bisphosphatase at 2.3 Å resolution [PDF]

, 1999
The three-dimensional structure of the R form of rabbit liver fructose 1,6-bisphosphatase (Fru-1,6-Pase; E.C. 3.1.3.11) has been determined by a combination of heavy-atom and molecular-replacement methods.
Erman, M., Ghosh, D., Jörnvall, H., Kaiser, R., Roszak, A.W., Weeks, C.M.   +5 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Prevalence, molecular characterization and antimicrobial resistance among Escherichia coli, Salmonella spp. and Staphylococcus aureus strains isolated from Egyptian broiler chicken flocks with omphalitis

Open Veterinary Journal
Background: Bacterial Omphalitis has been reported as a significant cause of mortalities in newly hatched broiler chicks. Aim: This study aimed at assessment of the occurrence of omphalitis among broiler chicken in Gharbia governorate in Egypt.
Rania Shaheen, Moshira El-Abasy, Hanem El-Sharkawy, Mahmoud M. Ismail   +3 more
doaj   +1 more source

Detection of Chlamydiaceae in Swiss wild birds sampled at a bird rehabilitation centre

Veterinary Record Open, 2020
Background Annually, 800–1500 wild birds are admitted to the rehabilitation centre of the Swiss Ornithological Institute, Sempach, Lucerne, Switzerland.
Nicole Borel, Sarah Albini, Sandro Stalder, Hanna Marti, Prisca Mattmann, Barbara Vogler, Nina Wolfrum   +6 more
doaj   +1 more source

Introduction and Expression of a Rabbit β-globin Gene in Mouse Fibroblasts [PDF]

, 1979
The cloned chromosomal rabbit ß-globin gene has been introduced into mouse fibroblasts by DNA-mediated gene transfer (transformation). In this report, we examine the expression of the rabbit gene in six independent transformants that contain from 1 to 20
Axel, R., Lacy, E., Maniatis, T., Silverstein, S., Wigler, M., Wold, B.   +5 more
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Blocking entry of hepatitis B and D viruses to hepatocytes as a novel immunotherapy for treating chronic infections [PDF]

, 2021
Background. Chronic hepatitis B and D virus (HBV/HDV) infections can cause cancer. Current HBV therapy using nucleoside analogues (NAs) is life-long and reduces but does not eliminate the risk of cancer.
Ahlén, G, Frelin, L, Jagya, N, Johansson, M, Maravelia, P, Meuleman, Philip, Ni, Y, Pasetto, A, Pater, L, Pérez, NC, Sällberg, M, Urban, S, Verch, G, Verhoye, Lieven   +13 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The Creation of a Multiallele Knockout Genotype in Rabbit Using CRISPR/Cas9 and Its Application in Translational Medicine

Applied Sciences, 2020
Nonrodent animal models have recently become more valuable in preclinical studies. The limitation of nonrodent animal models is that they must demonstrate relatively reliable and predictable responses in addition to representing complex etiologies of a ...
Tímea Pintér, Miklós Geiszt, Gábor L. Petheő, Máté Mihálffy, Gabriella Skoda, Nándor Lipták, Andrea Kerekes, Zsuzsanna Bősze, László Hiripi, Lilla Bodrogi   +9 more
doaj   +1 more source

A New Multiplex Real-Time RT-PCR for Simultaneous Detection and Differentiation of Avian Bornaviruses

Viruses, 2021
Avian bornaviruses were first described in 2008 as the causative agents of proventricular dilatation disease (PDD) in parrots and their relatives (Psittaciformes).
Brigitte Sigrist, Jessica Geers, Sarah Albini, Dennis Rubbenstroth, Nina Wolfrum   +4 more
doaj   +1 more source