Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Suggested Integral Analysis for Chaos-Based Image Cryptosystems. [PDF]
Murillo-Escobar MA+3 more
europepmc +1 more source
Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology
Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa+5 more
wiley +1 more source
Asymptomatic neonatal herpes simplex virus infection in mice leads to persistent CNS infection and long-term cognitive impairment. [PDF]
Dutton AJ+8 more
europepmc +1 more source
Museums and Digital Culture: From Reality to Digitality in the Age of Covid-19
Giannini T, Bowen JP.
europepmc +1 more source
PDLIM7 Synergizes With PDLIM2 and p62/Sqstm1 to Inhibit Inflammatory Signaling by Promoting Degradation of the p65 Subunit of NF-κB. [PDF]
Jodo A+4 more
europepmc +1 more source
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman+6 more
wiley +1 more source
Enhancing Key Management in LoRaWAN with Permissioned Blockchain. [PDF]
Ribeiro V+3 more
europepmc +1 more source
Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee+10 more
wiley +1 more source
Activation of AhR with nuclear IKKα regulates cancer stem-like properties in the occurrence of radioresistance. [PDF]
Yan B+24 more
europepmc +1 more source