Results 31 to 40 of about 2,701 (236)
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
SAFE-NET: Secure and Fast Encryption using Network of Pseudo-Random Number Generators [PDF]
, 2023 We propose a general framework to design a general class of random number generators suit- able for both computer simulation and computer security applications.
McCurdy, Jonathan
core +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim +8 more
wiley +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
An exhaustive review of the stream ciphers and their performance analysis [PDF]
The number of internet of things (IoT) applications has increased, which has increased the demand for low-resource gadgets. The data produced by these devices must be protected to guarantee security.
Ananth, Raghavendra +1 more
core +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
The mathematical models of modernstream ciphers [PDF]
, 2017 Дана робота присвячена аналізу сучасних потокових шифрів, а також методиці оцінювання поточних шифрів за наступними критеріями: шифрування довгих повідомлень, шифрування коротких повідомлень, ініціалізація / генерація ключових параметрів.This paper ...
Andrushkevych, Alina +3 more
core
Porting a Network Cryptographic Service to the RMC2000: A Case Study in Embedded Software Development [PDF]
, 2003 This paper describes our experience porting a transport-layer cryptography service to an embedded microcontroller. We describe some key development issues and techniques involved in porting networked software to a connected, limited resource device such ...
de Dios, Paolo +2 more
core +2 more sources
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source